ethyl 5-(cyclohexylmethyl)-1-(3-(2-hydroxypropan-2-yl)-5-(1-methylcyclopropyl)phenyl)-2,4-dimethyl-1H-pyrrole-3-carboxylate

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Chemical Name:ethyl 5-(cyclohexylmethyl)-1-(3-(2-hydroxypropan-2-yl)-5-(1-methylcyclopropyl)phenyl)-2,4-dimethyl-1H-pyrrole-3-carboxylate
CAS No.:1561965-21-6
Molecular Formula:C₂₉H₄₁NO₃
Molecular Weight:451.649
Hs Code.:

Synonyms:ethyl 5-(cyclohexylmethyl)-1-(3-(2-hydroxypropan-2-yl)-5-(1-methylcyclopropyl)phenyl)-2,4-dimethyl-1H-pyrrole-3-carboxylate

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Chemical Property of ethyl 5-(cyclohexylmethyl)-1-(3-(2-hydroxypropan-2-yl)-5-(1-methylcyclopropyl)phenyl)-2,4-dimethyl-1H-pyrrole-3-carboxylate

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Technology Process of ethyl 5-(cyclohexylmethyl)-1-(3-(2-hydroxypropan-2-yl)-5-(1-methylcyclopropyl)phenyl)-2,4-dimethyl-1H-pyrrole-3-carboxylate

There total 10 articles about ethyl 5-(cyclohexylmethyl)-1-(3-(2-hydroxypropan-2-yl)-5-(1-methylcyclopropyl)phenyl)-2,4-dimethyl-1H-pyrrole-3-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 1561965-18-1
ethyl 1-(3-(2-(benzyloxy)propan-2-yl)-5-(1-methylcyclopropyl)phenyl)-5-(cyclohexylmethyl)-2,4-dimethyl-1H-pyrrole-3-carboxylate

: 1561965-21-6
ethyl 5-(cyclohexylmethyl)-1-(3-(2-hydroxypropan-2-yl)-5-(1-methylcyclopropyl)phenyl)-2,4-dimethyl-1H-pyrrole-3-carboxylate

Guidance literature:: With palladium 10% on activated carbon; hydrogen; In methanol; at 20 ℃;

Reference yield:

: 1561965-14-7
C₃₀H₃₅NO₄

: 1561965-21-6
ethyl 5-(cyclohexylmethyl)-1-(3-(2-hydroxypropan-2-yl)-5-(1-methylcyclopropyl)phenyl)-2,4-dimethyl-1H-pyrrole-3-carboxylate

Guidance literature:: Multi-step reaction with 3 steps

1.1: tetrahydrofuran / 0 - 20 °C / Inert atmosphere

2.1: trifluoroacetic acid / dichloromethane / 0.17 h / 0 °C

2.2: 0.5 h / 0 °C

3.1: palladium 10% on activated carbon; hydrogen / methanol / 20 °C

With palladium 10% on activated carbon; hydrogen; trifluoroacetic acid; In tetrahydrofuran; methanol; dichloromethane;

Reference yield:

: 1561965-15-8
ethyl 1-(3-(2-(benzyloxy)propan-2-yl)-5-(1-methylcyclopropyl)phenyl)-5-(cyclohexyl(hydroxy)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxylate

: 1561965-21-6
ethyl 5-(cyclohexylmethyl)-1-(3-(2-hydroxypropan-2-yl)-5-(1-methylcyclopropyl)phenyl)-2,4-dimethyl-1H-pyrrole-3-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1.1: trifluoroacetic acid / dichloromethane / 0.17 h / 0 °C

1.2: 0.5 h / 0 °C

2.1: palladium 10% on activated carbon; hydrogen / methanol / 20 °C

With palladium 10% on activated carbon; hydrogen; trifluoroacetic acid; In methanol; dichloromethane;