HEXAKIS-(2,6-DI-O-PENTYL)-ALPHA-CYCLODEXTRIN

Base Information

• Chemical Name: HEXAKIS-(2,6-DI-O-PENTYL)-ALPHA-CYCLODEXTRIN
• CAS No.: 120336-45-0
• Molecular Formula: C₉₆H₁₈₀O₃₀
• Molecular Weight: 1814.47
• Mol file: 120336-45-0.mol

Synonyms:2,4,7,9,12,14,17,19,22,24,27,29-Dodecaoxaheptacyclo[26.2.2.23,6.28,11.213,16.218,21.223,26]dotetracontane,a-cyclodextrin deriv.;Hexakis(2,6-di-O-pentyl)-a-cyclodextrin

Chemical Property of HEXAKIS-(2,6-DI-O-PENTYL)-ALPHA-CYCLODEXTRIN

Chemical Property:

• PSA: 342.90000
• LogP: 13.51920

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of HEXAKIS-(2,6-DI-O-PENTYL)-ALPHA-CYCLODEXTRIN

There total 2 articles about HEXAKIS-(2,6-DI-O-PENTYL)-ALPHA-CYCLODEXTRIN which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 6.0%

1-Bromopentane (110-53-2) + alpha cyclodextrin (10016-20-3) → Hexakis(2,6-di-O-pentyl)-α-cyclodextrin (120336-45-0)

Guidance literature:

With sodium hydroxide; In dimethyl sulfoxide; at 23 ℃; for 72h;

DOI:10.1016/0008-6215(91)80033-J

Reference yield:

alpha cyclodextrin (10016-20-3) → Hexakis(2,6-di-O-pentyl)-α-cyclodextrin (120336-45-0) + Lipodex A (hexakis(2,3,6-tri-O-pentyl)cyclomaltohexaose) (115731-64-1) + 2,3-O-Pentylated α-cyclodextrin (133337-56-1) + 3,6-O-Pentylated α-cyclodextrin

Guidance literature:

With sodium hydroxide; In dimethyl sulfoxide; Title compound not separated from byproducts;

Reference yield:

acetic anhydride (108-24-7) + Hexakis(2,6-di-O-pentyl)-α-cyclodextrin (120336-45-0) → Lipodex B (hexakis(3-O-acetyl-2,6-di-O-pentyl)cyclomaltohexaose) (119037-99-9)

Guidance literature:

With dmap; triethylamine; In dichloromethane; for 96h; Heating;

DOI:10.1016/0008-6215(89)85164-X

upstream raw materials:

1-Bromopentane

alpha cyclodextrin

Downstream raw materials:

Lipodex B (hexakis(3-O-acetyl-2,6-di-O-pentyl)cyclomaltohexaose)

Refernces

• 1、 Ciucanu, Ionel,Negura, Simona,Hirschvogel, Werner,Luca, Constantin. "CHARACTERIZATION OF PER-O-ALKYLATED CYCLODEXTRINS BY GC/MS AS O-ALKYLATED GLUCONONITRILE ACETATES". . p. 843 - 848. Retrieved 2007/10/03.