tert-butyl cis-4-(3,4,5,6-tetrachlorophthaloylamino)cyclohexanepercarboxylate

Base Information

• Chemical Name: tert-butyl cis-4-(3,4,5,6-tetrachlorophthaloylamino)cyclohexanepercarboxylate
• CAS No.: 473435-69-7
• Molecular Formula: C₁₉H₁₉Cl₄NO₅
• Molecular Weight: 483.176
• Mol file: 473435-69-7.mol

Synonyms:tert-butyl cis-4-(3,4,5,6-tetrachlorophthaloylamino)cyclohexanepercarboxylate

Chemical Property of tert-butyl cis-4-(3,4,5,6-tetrachlorophthaloylamino)cyclohexanepercarboxylate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of tert-butyl cis-4-(3,4,5,6-tetrachlorophthaloylamino)cyclohexanepercarboxylate

There total 3 articles about tert-butyl cis-4-(3,4,5,6-tetrachlorophthaloylamino)cyclohexanepercarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

tert.-butylhydroperoxide (75-91-2) + cis-4-(3,4,5,6-tetrachlorophthaloylamino)cyclohexanecarboxylic acid (473435-63-1) → tert-butyl cis-4-(3,4,5,6-tetrachlorophthaloylamino)cyclohexanepercarboxylate (473435-69-7)

Guidance literature:

With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In decane; dichloromethane; at 20 ℃; for 2h;

DOI:10.1021/ja0263644

Reference yield:

tetrachlorophthalic anhydride (117-08-8) → tert-butyl cis-4-(3,4,5,6-tetrachlorophthaloylamino)cyclohexanepercarboxylate (473435-69-7)

Guidance literature:

Multi-step reaction with 2 steps

1: 65 percent / acetic acid / 8 h / 120 °C

2: 75 percent / N-ethyl-N'-dimethylaminopropyl carbodiimide hydrochloride; 4-(dimethylamino)pyridine / CH₂Cl₂; decane / 2 h / 20 °C

With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In decane; dichloromethane; acetic acid;

DOI:10.1021/ja0263644

Reference yield:

cis-4-aminocyclohexane-1-carboxylic acid (3685-23-2) → tert-butyl cis-4-(3,4,5,6-tetrachlorophthaloylamino)cyclohexanepercarboxylate (473435-69-7)

Guidance literature:

Multi-step reaction with 2 steps

1: 65 percent / acetic acid / 8 h / 120 °C

2: 75 percent / N-ethyl-N'-dimethylaminopropyl carbodiimide hydrochloride; 4-(dimethylamino)pyridine / CH₂Cl₂; decane / 2 h / 20 °C

With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In decane; dichloromethane; acetic acid;

DOI:10.1021/ja0263644

upstream raw materials:

tert.-butylhydroperoxide

cis-4-(3,4,5,6-tetrachlorophthaloylamino)cyclohexanecarboxylic acid

tetrachlorophthalic anhydride

cis-4-aminocyclohexane-1-carboxylic acid

Downstream raw materials:

tert-butoxy radical

Refernces