N,N'-(diselenodi-2,1-phenylenemethylene)bis<(2R,5R)-bis(benzyloxymethyl)pyrrolidine>

Base Information

• Chemical Name: N,N'-(diselenodi-2,1-phenylenemethylene)bis<(2R,5R)-bis(benzyloxymethyl)pyrrolidine>
• CAS No.: 156875-61-5
• Molecular Formula: C₅₄H₆₀N₂O₄Se₂
• Molecular Weight: 959.001
• Mol file: 156875-61-5.mol

Synonyms:N,N'-(diselenodi-2,1-phenylenemethylene)bis<(2R,5R)-bis(benzyloxymethyl)pyrrolidine>

Chemical Property of N,N'-(diselenodi-2,1-phenylenemethylene)bis<(2R,5R)-bis(benzyloxymethyl)pyrrolidine>

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N,N'-(diselenodi-2,1-phenylenemethylene)bis<(2R,5R)-bis(benzyloxymethyl)pyrrolidine>

There total 1 articles about N,N'-(diselenodi-2,1-phenylenemethylene)bis<(2R,5R)-bis(benzyloxymethyl)pyrrolidine> which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 53.0%

trans-(2R,5R)-bis(benzyloxymethyl)-pyrrolidine (127221-54-9) + bis<(2-chloromethyl)phenyl> diselenide (141819-08-1) → N,N'-(diselenodi-2,1-phenylenemethylene)bis<(2R,5R)-bis(benzyloxymethyl)pyrrolidine> (156875-61-5)

Guidance literature:

With sodium hydrogencarbonate; In N,N-dimethyl-formamide; at 80 ℃;

DOI:10.1246/cl.1994.923

Reference yield:

N,N'-(diselenodi-2,1-phenylenemethylene)bis<(2R,5R)-bis(benzyloxymethyl)pyrrolidine> (156875-61-5) → C27H30BrNO2Se (156875-72-8)

Guidance literature:

With bromine; In tetrachloromethane; Ambient temperature;

DOI:10.1246/cl.1994.923

Reference yield:

N,N'-(diselenodi-2,1-phenylenemethylene)bis<(2R,5R)-bis(benzyloxymethyl)pyrrolidine> (156875-61-5) → (2R,5R)-2,5-Bis-benzyloxymethyl-1-[2-((1R,2S)-2-methoxy-1-methyl-2-phenyl-ethylselanyl)-benzyl]-pyrrolidine

Guidance literature:

Multi-step reaction with 2 steps

1: Br₂ / CCl₄; CH₂Cl₂ / 0.5 h / Ambient temperature

2: CH₂Cl₂ / -78 deg C to room temperature, overnight

With bromine; In tetrachloromethane; dichloromethane;

DOI:10.1016/S0040-4020(96)01166-0

upstream raw materials:

trans-(2R,5R)-bis(benzyloxymethyl)-pyrrolidine

bis<(2-chloromethyl)phenyl> diselenide

Downstream raw materials:

C₂₇H₃₀BrNO₂Se