(E)-1-(4-methoxyphenyl)-5-phenyl-3-styryl-4,5-dihydro-1Hpyrazole

Base Information

• Chemical Name: (E)-1-(4-methoxyphenyl)-5-phenyl-3-styryl-4,5-dihydro-1Hpyrazole
• CAS No.: 71630-17-6
• Molecular Formula: C₂₄H₂₂N₂O
• Molecular Weight: 354.451
• Mol file: 71630-17-6.mol

Synonyms:(E)-1-(4-methoxyphenyl)-5-phenyl-3-styryl-4,5-dihydro-1Hpyrazole

Chemical Property of (E)-1-(4-methoxyphenyl)-5-phenyl-3-styryl-4,5-dihydro-1Hpyrazole

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (E)-1-(4-methoxyphenyl)-5-phenyl-3-styryl-4,5-dihydro-1Hpyrazole

There total 2 articles about (E)-1-(4-methoxyphenyl)-5-phenyl-3-styryl-4,5-dihydro-1Hpyrazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 66.0%

4-methoxyphenylhydrazine hydrochloric acid salt + dibenzylideneacetone (35225-79-7) → (E)-1-(4-methoxyphenyl)-5-phenyl-3-styryl-4,5-dihydro-1Hpyrazole (71630-17-6)

Guidance literature:

With acetic acid; In ethanol; Reflux;

DOI:10.1016/j.bioorg.2020.103780

Reference yield:

benzaldehyde (100-52-7) → (E)-1-(4-methoxyphenyl)-5-phenyl-3-styryl-4,5-dihydro-1Hpyrazole (71630-17-6)

Guidance literature:

Multi-step reaction with 2 steps

1: sodium hydroxide / ethanol / 1.5 h / 20 °C

2: acetic acid / ethanol / Reflux

With acetic acid; sodium hydroxide; In ethanol; 1: |Claisen-Schmidt Condensation;

DOI:10.1016/j.bioorg.2020.103780

upstream raw materials:

dibenzylideneacetone

benzaldehyde