(S)-4-((R)-4-Benzyl-2-oxo-oxazolidin-3-yl)-3-cyclopropyl-4-oxo-butyraldehyde

Base Information

Chemical Name:(S)-4-((R)-4-Benzyl-2-oxo-oxazolidin-3-yl)-3-cyclopropyl-4-oxo-butyraldehyde
CAS No.:691876-09-2
Molecular Formula:C₁₇H₁₉NO₄
Molecular Weight:301.342
Hs Code.:

Synonyms:(S)-4-((R)-4-Benzyl-2-oxo-oxazolidin-3-yl)-3-cyclopropyl-4-oxo-butyraldehyde

Suppliers and Price of (S)-4-((R)-4-Benzyl-2-oxo-oxazolidin-3-yl)-3-cyclopropyl-4-oxo-butyraldehyde

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (S)-4-((R)-4-Benzyl-2-oxo-oxazolidin-3-yl)-3-cyclopropyl-4-oxo-butyraldehyde

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (S)-4-((R)-4-Benzyl-2-oxo-oxazolidin-3-yl)-3-cyclopropyl-4-oxo-butyraldehyde

There total 3 articles about (S)-4-((R)-4-Benzyl-2-oxo-oxazolidin-3-yl)-3-cyclopropyl-4-oxo-butyraldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 691876-08-1
(R)-4-Benzyl-3-((S)-2-cyclopropyl-4,4-dimethoxy-butyryl)-oxazolidin-2-one

: 691876-09-2
(S)-4-((R)-4-Benzyl-2-oxo-oxazolidin-3-yl)-3-cyclopropyl-4-oxo-butyraldehyde

Guidance literature:: With trifluoroacetic acid;

Reference yield:

: 909717-31-3
2-cyclopropyl-4,4-dimethoxy-butyric acid

: 691876-09-2
(S)-4-((R)-4-Benzyl-2-oxo-oxazolidin-3-yl)-3-cyclopropyl-4-oxo-butyraldehyde

Guidance literature:: Multi-step reaction with 2 steps

1.1: tBuCOCl; DIEA / tetrahydrofuran

1.2: tetrahydrofuran

2.1: 93 percent / aq. TFA

With pivaloyl chloride; N-ethyl-N,N-diisopropylamine; trifluoroacetic acid; In tetrahydrofuran;
DOI:10.1016/j.bmcl.2006.07.011

Reference yield:

: 5239-82-7
cyclopropylacetic acid

: 691876-09-2
(S)-4-((R)-4-Benzyl-2-oxo-oxazolidin-3-yl)-3-cyclopropyl-4-oxo-butyraldehyde

Guidance literature:: Multi-step reaction with 3 steps

1.1: LDA / tetrahydrofuran / -78 - 40 °C

2.1: tBuCOCl; DIEA / tetrahydrofuran

2.2: tetrahydrofuran

3.1: 93 percent / aq. TFA

With pivaloyl chloride; N-ethyl-N,N-diisopropylamine; trifluoroacetic acid; lithium diisopropyl amide; In tetrahydrofuran;
DOI:10.1016/j.bmcl.2006.07.011