methyl (S,S,S)-2-amino-5-phenylcyclopentane-1-carboxylate

Base Information

• Chemical Name: methyl (S,S,S)-2-amino-5-phenylcyclopentane-1-carboxylate
• CAS No.: 1448055-26-2
• Molecular Formula: C₁₃H₁₇NO₂
• Molecular Weight: 219.283
• Mol file: 1448055-26-2.mol

Synonyms:methyl (S,S,S)-2-amino-5-phenylcyclopentane-1-carboxylate

Chemical Property of methyl (S,S,S)-2-amino-5-phenylcyclopentane-1-carboxylate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of methyl (S,S,S)-2-amino-5-phenylcyclopentane-1-carboxylate

There total 10 articles about methyl (S,S,S)-2-amino-5-phenylcyclopentane-1-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

methyl (S,S,S,S)-2-[N-benzyl-N-(α-methylbenzyl)amino]-5-phenylcyclopent-3-ene-1-carboxylate (1448055-23-9) → methyl (S,S,S)-2-amino-5-phenylcyclopentane-1-carboxylate (1448055-26-2)

Guidance literature:

With palladium on activated charcoal; hydrogen; In methanol; at 20 ℃; for 24h; under 760.051 Torr;

DOI:10.1039/c3cc43250e

Reference yield: 61.0%

methyl (S,S,S,S)-2-[N-benzyl-N-(α-methylbenzyl)amino]-5-phenylcyclopentane-1-carboxylate → methyl (S,S,S)-2-amino-5-phenylcyclopentane-1-carboxylate (1448055-26-2)

Guidance literature:

With 10 wt% Pd(OH)2 on carbon; hydrogen; In methanol; at 20 ℃; for 24h; under 760.051 Torr;

Reference yield:

methyl (S,S,S,S,E)-2-(1'-phenylprop-2'-en-1'-yl)-3-[N-benzyl-N-(α-methylbenzyl)amino]hex-4-enoate (1448055-17-1) → methyl (S,S,S)-2-amino-5-phenylcyclopentane-1-carboxylate (1448055-26-2)

Guidance literature:

Multi-step reaction with 2 steps

1: Grubbs catalyst first generation / dichloromethane / 24 h / 40 °C

2: hydrogen; palladium on activated charcoal / methanol / 24 h / 20 °C / 760.05 Torr

With Grubbs catalyst first generation; palladium on activated charcoal; hydrogen; In methanol; dichloromethane; 1: |Grubbs Olefin Metathesis;

DOI:10.1039/c3cc43250e

upstream raw materials:

methyl (S,S,S,S,E)-2-(1'-phenylprop-2'-en-1'-yl)-3-[N-benzyl-N-(α-methylbenzyl)amino]hex-4-enoate

methyl (S,S,S,S)-2-[N-benzyl-N-(α-methylbenzyl)amino]-5-phenylcyclopent-3-ene-1-carboxylate

C₃₀H₃₃NO₂

5-hydroxycyclopent-1-enecarboxylic acid methyl ester