N-(2-aminophenyl)-N-(2-phenylethyl)amine hydrochloride

Base Information

• Chemical Name: N-(2-aminophenyl)-N-(2-phenylethyl)amine hydrochloride
• CAS No.: 41625-94-9
• Molecular Formula: C14H16 N2
• Molecular Weight: 212.294
• European Community (EC) Number: 807-800-6
• DSSTox Substance ID: DTXSID20596157
• Mol file: 41625-94-9.mol

Synonyms:N-(2-aminophenyl)-N-(2-phenylethyl)amine hydrochloride;41625-94-9;1189984-54-0;1-N-(2-phenylethyl)benzene-1,2-diamine hydrochloride;2-N-(2-phenylethyl)benzene-1,2-diamine;hydrochloride;N1-Phenethylbenzene-1,2-diamine hydrochloride;DTXSID20596157;DB-119876;CS-0218806;EN300-02085;G33416;SR-01000028416;SR-01000028416-1;N1-(2-phenylethyl)benzene-1,2-diamine hydrochloride;N-(2-AMINOPHENYL)-N-(2-PHENYLETHYL)AMINEHYDROCHLORIDE;N~1~-(2-Phenylethyl)benzene-1,2-diamine--hydrogen chloride (1/1)

Chemical Property of N-(2-aminophenyl)-N-(2-phenylethyl)amine hydrochloride

Chemical Property:

• Vapor Pressure: 1.02E-06mmHg at 25°C
• Boiling Point: 403.4°C at 760 mmHg
• Flash Point: 233.8°C
• Density: 1.126g/cm³
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 4
• Exact Mass: 248.1080262
• Heavy Atom Count: 17
• Complexity: 187

Purity/Quality:

N-(2-AMINOPHENYL)-N-(2-PHENYLETHYL)AMINE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)CCNC2=CC=CC=C2N.Cl

Technology Process of N-(2-aminophenyl)-N-(2-phenylethyl)amine hydrochloride

There total 5 articles about N-(2-aminophenyl)-N-(2-phenylethyl)amine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

N-(2-Phenylethyl)-2-nitroaniline (100870-32-4) → N-(2-phenylethyl)-2-aminoaniline (41625-94-9)

Guidance literature:

With Aminoiminomethanesulfinic acid; sodium hydroxide; In ethanol; water; at 50 ℃; for 1.5h;

DOI:10.1016/j.tetlet.2020.151599

Reference yield:

phenethylamine (64-04-0) → N-(2-phenylethyl)-2-aminoaniline (41625-94-9)

Guidance literature:

Multi-step reaction with 2 steps

2: Na₂S₂O₄; aq.-ethanolic KOH

With potassium hydroxide; sodium dithionite;

DOI:10.1039/jr9570004559

Reference yield:

ortho-nitrofluorobenzene (1493-27-2,127723-77-7) → N-(2-phenylethyl)-2-aminoaniline (41625-94-9)

Guidance literature:

Multi-step reaction with 2 steps

1: potassium carbonate / N,N-dimethyl-formamide / 60 °C

2: acetic acid; zinc / methanol / 20 °C

With potassium carbonate; acetic acid; zinc; In methanol; N,N-dimethyl-formamide;

DOI:10.1016/j.bioorg.2015.05.005

upstream raw materials:

N-(2-Phenylethyl)-2-nitroaniline

phenethylamine

2-Chloronitrobenzene

ortho-nitrofluorobenzene

Downstream raw materials:

1-phenethyl-2-phenyl-1H-benzo[d]imidazole

C₂₄H₂₀N₂O₂

2-Chloromethyl-1-phenethyl-1H-benzoimidazole

1-phenethyl-1H-benzo[d][1,2,3]triazole