2-[1-(tert-butyl-dimethyl-silanyloxy)-2-phenyl-penta-2,4-dienyl]-pyridine

Base Information

• Chemical Name: 2-[1-(tert-butyl-dimethyl-silanyloxy)-2-phenyl-penta-2,4-dienyl]-pyridine
• CAS No.: 924651-29-6
• Molecular Formula: C₂₂H₂₉NOSi
• Molecular Weight: 351.564
• Mol file: 924651-29-6.mol

Synonyms:2-[1-(tert-butyl-dimethyl-silanyloxy)-2-phenyl-penta-2,4-dienyl]-pyridine

Chemical Property of 2-[1-(tert-butyl-dimethyl-silanyloxy)-2-phenyl-penta-2,4-dienyl]-pyridine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

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Technology Process of 2-[1-(tert-butyl-dimethyl-silanyloxy)-2-phenyl-penta-2,4-dienyl]-pyridine

There total 1 articles about 2-[1-(tert-butyl-dimethyl-silanyloxy)-2-phenyl-penta-2,4-dienyl]-pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-phenyl-1-pyridin-2-yl-penta-2,4-dien-1-ol (924651-06-9) + tert-butyldimethylsilyl chloride (18162-48-6) → 2-[1-(tert-butyl-dimethyl-silanyloxy)-2-phenyl-penta-2,4-dienyl]-pyridine (924651-29-6)

Guidance literature:

With 1H-imidazole; In N,N-dimethyl-formamide; at 20 ℃; for 4h;

DOI:10.1021/ja0673027

Reference yield:

2-[1-(tert-butyl-dimethyl-silanyloxy)-2-phenyl-penta-2,4-dienyl]-pyridine (924651-29-6) + trans-1,4-diacetoxy-2-butene (1576-98-3) → (Z)-acetic acid 6-(tert-butyl-dimethyl-silanyloxy)-5-phenyl-6-pyridin-2-yl-hexa-2,4-dienyl ester + (E)-acetic acid 6-(tert-butyl-dimethyl-silanyloxy)-5-phenyl-6-pyridin-2-yl-hexa-2,4-dienyl ester

Guidance literature:

Grubbs catalyst first generation; In toluene; at 100 ℃; for 12h; Title compound not separated from byproducts;

DOI:10.1021/ja0673027

Reference yield:

2-[1-(tert-butyl-dimethyl-silanyloxy)-2-phenyl-penta-2,4-dienyl]-pyridine (924651-29-6) → (E)-(S)-4-(tert-Butyl-dimethyl-silanyloxy)-3-phenyl-4-pyridin-2-yl-but-2-enal (924651-31-0)

Guidance literature:

With sodium periodate; osmium(VIII) oxide; In tetrahydrofuran; water; for 4h;

DOI:10.1021/ja0673027

upstream raw materials:

2-phenyl-1-pyridin-2-yl-penta-2,4-dien-1-ol

tert-butyldimethylsilyl chloride

Downstream raw materials:

(E)-(S)-4-(tert-Butyl-dimethyl-silanyloxy)-3-phenyl-4-pyridin-2-yl-but-2-enal