2-N-methyl-N-phenylaminobenzoxazole

Base Information

• Chemical Name: 2-N-methyl-N-phenylaminobenzoxazole
• CAS No.: 136540-09-5
• Molecular Formula: C₁₄H₁₂N₂O
• Molecular Weight: 224.262
• Mol file: 136540-09-5.mol

Synonyms:2-N-methyl-N-phenylaminobenzoxazole

Chemical Property of 2-N-methyl-N-phenylaminobenzoxazole

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of 2-N-methyl-N-phenylaminobenzoxazole

There total 9 articles about 2-N-methyl-N-phenylaminobenzoxazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

2-chloro-1,3-benzoxazole (615-18-9) + N,N-dimethyl-aniline (121-69-7,77733-26-7) → 2-N-methyl-N-phenylaminobenzoxazole (136540-09-5)

Guidance literature:

In tetrahydrofuran; at 100 ℃; for 96h; under 6000480 Torr;

DOI:10.1246/cl.1991.1283

Reference yield: 88.0%

benzoxazole (273-53-0,29791-96-6) + N-methylaniline (100-61-8) → 2-N-methyl-N-phenylaminobenzoxazole (136540-09-5)

Guidance literature:

With copper acetylacetonate; oxygen; In 5,5-dimethyl-1,3-cyclohexadiene; at 140 ℃; for 18h;

DOI:10.1016/j.tetlet.2012.09.064

Reference yield: 78.0%

2-chloro-1,3-benzoxazole (615-18-9) + N-methylaniline (100-61-8) → 2-N-methyl-N-phenylaminobenzoxazole (136540-09-5)

Guidance literature:

With N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; at 110 ℃; for 12h;

DOI:10.1002/cjoc.202100658

upstream raw materials:

benzo[d]oxazole-2-(3H)-thione

N-methylaniline

N-phenyl-1,3-benzoxazol-2-amine

methyl iodide