Technology Process of 1H-Benzimidazole-2-carboxaldehyde,5,6-difluoro-1-methyl-(9CI)
There total 5 articles about 1H-Benzimidazole-2-carboxaldehyde,5,6-difluoro-1-methyl-(9CI) which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 3 steps
1: acetic acid / methanol / 16 h / 20 °C
2: N,N-dimethyl-formamide / 16 h / 20 °C
3: hydrogenchloride / water / 6 h / 60 °C
With
hydrogenchloride; acetic acid;
In
methanol; water; N,N-dimethyl-formamide;
- Guidance literature:
-
With
hydrogenchloride;
In
water;
at 60 ℃;
for 6h;
- Guidance literature:
-
Multi-step reaction with 4 steps
1: hydrogen / palladium 10% on activated carbon / methanol / 3 h / 20 °C
2: acetic acid / methanol / 16 h / 20 °C
3: N,N-dimethyl-formamide / 16 h / 20 °C
4: hydrogenchloride / water / 6 h / 60 °C
With
hydrogenchloride; hydrogen; acetic acid;
palladium 10% on activated carbon;
In
methanol; water; N,N-dimethyl-formamide;