O-(2-CARBOXYETHYL)POLYETHYLENE GLYCOL 3,400

Base Information

• Chemical Name: O-(2-CARBOXYETHYL)POLYETHYLENE GLYCOL 3,400
• CAS No.: 117786-94-4
• Molecular Formula: C₅H₁₀O₄
• Molecular Weight: 134.132

Synonyms:O-(2-CARBOXYETHYL)POLYETHYLENE GLYCOL 3,400;POLY-ETHYLENE GLYCOL 3,400 MONOACID;O-(2-Carboxyethyl)polyethylene glycol 5000;O-(2-Carboxyethyl)polyethylene glycol 10000;O-(2-Carboxyethyl)polyethylene glycol;O-(2-Carboxyethyl)polyethylene glycol 3,000

Chemical Property of O-(2-CARBOXYETHYL)POLYETHYLENE GLYCOL 3,400

Chemical Property:

• PSA: 0.00000
• LogP: 0.00000
• Storage Temp.: −20°C

Purity/Quality:

98%,99%, ^*data from raw suppliers

O-(2-Carboxyethyl)polyethylene glycol 3,000 ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Reactant for:? ;Preparation of multifunctional polymeric micelles for antiviral treatment1? ;Preparation of NO-pegylated epirubicin as a chemotherapy agent2? ;Preparation of functionalized oligomers and copolymers with terpyridine-metal complexing segments3 O-(2-Carboxyethyl)polyethylene glycol is a reactant involved in: ?Preparation of multifunctional polymeric micelles for antiviral treatment ?Modulating the properties of chemotherapy agents ?Increasing the sensitivity of carboxyl-terminated dendrimer-coated bioactive interfaces for protein microarrays ?Studies of therapeutic usefulness for receptor-targeted blockage of oxidized low density lipoprotein uptake

Technology Process of O-(2-CARBOXYETHYL)POLYETHYLENE GLYCOL 3,400

There total 5 articles about O-(2-CARBOXYETHYL)POLYETHYLENE GLYCOL 3,400 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

3-[2-(2-benzyloxyethoxy)ethoxy]propanoic acid (127457-63-0) → 3-(2-(2-hydroxyethoxy)ethoxy)propanoic acid (117786-94-4)

Guidance literature:

With 1% Pd/C; hydrogen; In tetrahydrofuran; for 24h;

DOI:10.1016/j.bmcl.2010.04.049

Reference yield: 90.0%

→ 3-(2-(2-hydroxyethoxy)ethoxy)propanoic acid (117786-94-4)

Guidance literature:

Reference yield:

3-{2-[2-(2-hydroxy-ethoxy)-ethoxy]-ethoxy}-propionic acid tert-butyl ester (186020-66-6,892154-71-1) → 3-{2-[2-(2-hydroxyethoxyl)ethoxy]ethoxy}propanoic acid (518044-49-0,117786-94-4)

Guidance literature:

With trifluoroacetic acid; In 4-(dicyanomethylene)-2-methyl-6-(p-dimethylaminostyryl)-4H-pyran;

upstream raw materials:

3-[2-(2-benzyloxyethoxy)ethoxy]propanoic acid

3-{2-[2-(2-hydroxy-ethoxy)-ethoxy]-ethoxy}-propionic acid tert-butyl ester

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