tert-Butyl 12-hydroxy-4,7,10-trioxadodecanoate

Base Information Edit

Chemical Name:tert-Butyl 12-hydroxy-4,7,10-trioxadodecanoate
CAS No.:186020-66-6
Molecular Formula:C13H26O6
Molecular Weight:278.346
Hs Code.:2918990090
European Community (EC) Number:886-523-2
DSSTox Substance ID:DTXSID50394426
Wikidata:Q72483995
Mol file:186020-66-6.mol

Synonyms:186020-66-6;tert-Butyl 12-hydroxy-4,7,10-trioxadodecanoate;Hydroxy-PEG3-t-butyl ester;tert-Butyl 3-(2-(2-(2-hydroxyethoxy)ethoxy)ethoxy)propanoate;HO-PEG3-CH2CH2COOtBu;Hydroxy-PEG3-(CH2)2-Boc;Tert-butyl 3-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]propanoate;MFCD03791106;tert-Butyl 3-[2-(2-(2-hydroxyethoxy)ethoxy)ethoxy]propionate;TERT-BUTYL 3-{2-[2-(2-HYDROXYETHOXY)ETHOXY]ETHOXY}PROPANOATE;3-[2-[2-(2-Hydroxyethoxy)ethoxy]ethoxy]propionic acid tert-butyl ester;OH-PEG3-TBA;OH-PEG3-CH2CH2COOtBu;tert-Butyl triethylene glycol-O-propionate;HO-PEG3-t-butyl ester;SCHEMBL40466;DTXSID50394426;KSXVEOLRERRELV-UHFFFAOYSA-N;CS-B1507;ZB0942;AKOS022183352;GS-6238;AM803415;BP-20633;HY-42488;SY107489;B5587;FT-0734452;t-butyl 12-hydroxy-4,7,10-trioxadodecanoate;tert-Butyl12-hydroxy-4,7,10-trioxadodecanoate;EN300-7421448;TERT-BUTYL 12-HYDROXY-4 7 10-TRIOXA-;A880689;J-011940;12-Hydroxy-4,7,10-trioxadodecanoic Acid tert-Butyl Ester;tert-butyl 3-(2-(2-(2-hydroxyethoxyl)ethoxy)ethoxy)propanoate;tert-Butyl 12-hydroxy-4,7,10-trioxadodecanoate, >=97.0% (GC);3-{2-[2-(2-Hydroxy-ethoxy)-ethoxy]-ethoxy}-propionic acid tert-butyl ester;tert-Butyl 12-Hydroxy-4,7,10-trioxadodecanoate

Suppliers and Price of tert-Butyl 12-hydroxy-4,7,10-trioxadodecanoate

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
tert-Butyl 12-hydroxy-4,7,10-trioxadodecanoate
100mg
$ 60.00

TRC
tert-Butyl 12-hydroxy-4,7,10-trioxadodecanoate
500mg
$ 110.00

TCI Chemical
tert-Butyl 12-Hydroxy-4,7,10-trioxadodecanoate >97.0%(GC)
1g
$ 74.00

TCI Chemical
tert-Butyl 12-Hydroxy-4,7,10-trioxadodecanoate >97.0%(GC)
5g
$ 255.00

Sigma-Aldrich
tert-Butyl 12-hydroxy-4,7,10-trioxadodecanoate ≥97.0%(GC)
5 g
$ 267.00

Sigma-Aldrich
tert-Butyl 12-hydroxy-4,7,10-trioxadodecanoate ≥97.0% (GC)
5g-f
$ 261.00

Sigma-Aldrich
Hydroxy-PEG4-t-butyl ester
1 g
$ 232.00

Sigma-Aldrich
tert-Butyl 12-hydroxy-4,7,10-trioxadodecanoate ≥97.0%(GC)
1 g
$ 81.80

Sigma-Aldrich
Hydroxy-PEG4-t-butyl ester
250 mg
$ 80.40

Sigma-Aldrich
tert-Butyl 12-hydroxy-4,7,10-trioxadodecanoate ≥97.0% (GC)
1g-f
$ 79.80

Total 33 raw suppliers

Chemical Property of tert-Butyl 12-hydroxy-4,7,10-trioxadodecanoate Edit

Chemical Property:

Vapor Pressure:7.78E-07mmHg at 25°C
Refractive Index:n20/D 1.446
Boiling Point:365.8oC at 760 mmHg
PKA:14.36±0.10(Predicted)
Flash Point:125.2oC
PSA：74.22000
Density:1.057g/cm3
LogP:0.76030
Storage Temp.:Inert atmosphere,Room Temperature
XLogP3:-0.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:13
Exact Mass:278.17293854
Heavy Atom Count:19
Complexity:224

Purity/Quality:

98% ^*data from raw suppliers

tert-Butyl 12-hydroxy-4,7,10-trioxadodecanoate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)CCOCCOCCOCCO
Description Hydroxy-PEG3-t-butyl ester is a PEG linker containing a hydroxyl group with a t-butyl ester. The hydrophilic PEG spacer increases solubility in aqueous media. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. The t-butyl protected carboxyl group can be deprotected under acidic conditions.

Technology Process of tert-Butyl 12-hydroxy-4,7,10-trioxadodecanoate

There total 2 articles about tert-Butyl 12-hydroxy-4,7,10-trioxadodecanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 1663-39-4,25232-27-3
tert-Butyl acrylate

: 112-27-6
2,2'-[1,2-ethanediylbis(oxy)]bisethanol

: 186020-66-6,892154-71-1
3-{2-[2-(2-hydroxy-ethoxy)-ethoxy]-ethoxy}-propionic acid tert-butyl ester

Guidance literature:: 2,2'-[1,2-ethanediylbis(oxy)]bisethanol; With sodium; In tetrahydrofuran; at 20 ℃;

tert-Butyl acrylate; In tetrahydrofuran; at 20 ℃; for 20h;

With hydrogenchloride; water; In tetrahydrofuran;