Technology Process of ethyl 4-((2-hydroxyphenyl)ethynyl)benzoate
There total 5 articles about ethyl 4-((2-hydroxyphenyl)ethynyl)benzoate which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
hydrogenchloride;
In
tetrahydrofuran; water; isopropyl alcohol;
at 20 ℃;
for 24h;
Inert atmosphere;
DOI:10.1039/c6cc01690a
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: sodium hydride / tetrahydrofuran; mineral oil / 0.08 h / 0 °C / Inert atmosphere
1.2: 24 h / 0 - 20 °C / Inert atmosphere
2.1: bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine / 50 °C / Inert atmosphere
3.1: hydrogenchloride / tetrahydrofuran; isopropyl alcohol; water / 24 h / 20 °C / Inert atmosphere
With
hydrogenchloride; bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; sodium hydride; triethylamine;
In
tetrahydrofuran; water; isopropyl alcohol; mineral oil;
DOI:10.1039/c6cc01690a
- Guidance literature:
-
Multi-step reaction with 2 steps
1: bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine / 50 °C / Inert atmosphere
2: hydrogenchloride / tetrahydrofuran; isopropyl alcohol; water / 24 h / 20 °C / Inert atmosphere
With
hydrogenchloride; bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine;
In
tetrahydrofuran; water; isopropyl alcohol;
DOI:10.1039/c6cc01690a
