7-bromo-4-hydroxy-1H-indole-3-carbaldehyde

Base Information

Chemical Name:7-bromo-4-hydroxy-1H-indole-3-carbaldehyde
CAS No.:404887-98-5
Molecular Formula:C₉H₆BrNO₂
Molecular Weight:240.056
Hs Code.:
DSSTox Substance ID:DTXSID501258823
Nikkaji Number:J1.648.256K

Synonyms:7-bromo-4-hydroxy-1H-indole-3-carbaldehyde;404887-98-5;DTXSID501258823;4-Hydroxy-7-bromo-1H-indole-3-carbaldehyde;7-Bromo-4-hydroxy-1H-indole-3-carboxaldehyde

Suppliers and Price of 7-bromo-4-hydroxy-1H-indole-3-carbaldehyde

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Alichem
7-bromo-4-hydroxy-1H-indole-3-carbaldehyde
10g
$ 3456.40

Alichem
7-bromo-4-hydroxy-1H-indole-3-carbaldehyde
1g
$ 1046.25

Total 1 raw suppliers

Chemical Property of 7-bromo-4-hydroxy-1H-indole-3-carbaldehyde

Chemical Property:

XLogP3:1.8
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:238.95819
Heavy Atom Count:13
Complexity:212

Purity/Quality:: 7-bromo-4-hydroxy-1H-indole-3-carbaldehyde ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC(=C2C(=C1O)C(=CN2)C=O)Br

Technology Process of 7-bromo-4-hydroxy-1H-indole-3-carbaldehyde

There total 2 articles about 7-bromo-4-hydroxy-1H-indole-3-carbaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 10.0%

: 81779-27-3
4-Hydroxyindole-3-carbaldehyde

: 5-bromo-4-hydroxyindole-3-carbaldehyde

: 404887-98-5
7-bromo-4-hydroxyindole-3-carbaldehyde

Guidance literature:: With pyridinium perbromide hydrobromide; In tetrahydrofuran; chloroform; at 20 ℃; for 1h;
DOI:10.1248/cpb.50.92

Reference yield:

: 7042-71-9
4-benzyloxyindole-3-carbaldehyde

: 404887-98-5
7-bromo-4-hydroxyindole-3-carbaldehyde

Guidance literature:: Multi-step reaction with 2 steps

1: 76 percent / H₂ / 10 percent Pd/C / methanol / 1 h / 20 °C

2: 84 percent / Py*HBr*Br₂ / CHCl₃; tetrahydrofuran / 1 h / 20 °C

With pyridinium perbromide hydrobromide; hydrogen; palladium on activated charcoal; In tetrahydrofuran; methanol; chloroform;
DOI:10.1248/cpb.50.92