Technology Process of C15H15BrClNO4
There total 8 articles about C15H15BrClNO4 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
sodium hydride;
In
paraffin oil;
at 20 ℃;
for 6.5h;
DOI:10.1021/ol401710a
- Guidance literature:
-
Multi-step reaction with 6 steps
1.1: dichloromethane / 16.5 h / 0 - 20 °C
2.1: magnesium sulfate heptahydrate; potassium permanganate / water / 3 h / Reflux
3.1: sodium hydroxide / water / 5 h / Reflux
4.1: pyridine / dichloromethane; acetonitrile / 3 h / 50 °C
5.1: sodium hydride / N,N-dimethyl-formamide; paraffin oil / 0.75 h / Cooling with ice
5.2: 5 h / 20 °C
6.1: sodium hydride / paraffin oil / 6.5 h / 20 °C
With
pyridine; potassium permanganate; magnesium sulfate heptahydrate; sodium hydride; sodium hydroxide;
In
dichloromethane; water; N,N-dimethyl-formamide; acetonitrile; paraffin oil;
DOI:10.1021/ol401710a
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: magnesium sulfate heptahydrate; potassium permanganate / water / 3 h / Reflux
2.1: sodium hydroxide / water / 5 h / Reflux
3.1: pyridine / dichloromethane; acetonitrile / 3 h / 50 °C
4.1: sodium hydride / N,N-dimethyl-formamide; paraffin oil / 0.75 h / Cooling with ice
4.2: 5 h / 20 °C
5.1: sodium hydride / paraffin oil / 6.5 h / 20 °C
With
pyridine; potassium permanganate; magnesium sulfate heptahydrate; sodium hydride; sodium hydroxide;
In
dichloromethane; water; N,N-dimethyl-formamide; acetonitrile; paraffin oil;
DOI:10.1021/ol401710a
