(E)-N-(6-Amino-1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydro-pyrimidin-5-yl)-3-(2,3-dimethoxy-phenyl)-acrylamide

Base Information

Chemical Name:(E)-N-(6-Amino-1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydro-pyrimidin-5-yl)-3-(2,3-dimethoxy-phenyl)-acrylamide
CAS No.:1026126-04-4
Molecular Formula:C₁₇H₂₀N₄O₅
Molecular Weight:360.37
Hs Code.:

Synonyms:(E)-N-(6-Amino-1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydro-pyrimidin-5-yl)-3-(2,3-dimethoxy-phenyl)-acrylamide

Suppliers and Price of (E)-N-(6-Amino-1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydro-pyrimidin-5-yl)-3-(2,3-dimethoxy-phenyl)-acrylamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (E)-N-(6-Amino-1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydro-pyrimidin-5-yl)-3-(2,3-dimethoxy-phenyl)-acrylamide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of (E)-N-(6-Amino-1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydro-pyrimidin-5-yl)-3-(2,3-dimethoxy-phenyl)-acrylamide

There total 1 articles about (E)-N-(6-Amino-1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydro-pyrimidin-5-yl)-3-(2,3-dimethoxy-phenyl)-acrylamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 5440-00-6
4,5-Diamino-1,3-dimethyluracil

: 7345-82-6
trans-2,3-dimethoxycinnamic acid

: 1026126-04-4
(E)-N-(6-Amino-1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydro-pyrimidin-5-yl)-3-(2,3-dimethoxy-phenyl)-acrylamide

Guidance literature:: With 1H-imidazole; dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In N,N-dimethyl-formamide; for 3h; Ambient temperature;
DOI:10.1021/jm00062a005

Reference yield:

: 1026126-04-4
(E)-N-(6-Amino-1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydro-pyrimidin-5-yl)-3-(2,3-dimethoxy-phenyl)-acrylamide

: 147700-16-1
1,3-Dimethyl-8-(2,3-dimethoxystyryl)xanthine

Guidance literature:: With sodium hydroxide; In methanol; at 60 ℃; for 2h; Yield given;
DOI:10.1021/jm00062a005

Reference yield:

: 1026126-04-4
(E)-N-(6-Amino-1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydro-pyrimidin-5-yl)-3-(2,3-dimethoxy-phenyl)-acrylamide

: 147700-17-2
1,3,7-Trimethyl-8-(2,3-dimethoxystyryl)xanthine

Guidance literature:: Multi-step reaction with 2 steps

1: 4 N aq. NaOH / methanol / 2 h / 60 °C

2: 49 percent / K₂CO₃ / dimethylformamide / 0.5 h / 60 °C

With sodium hydroxide; potassium carbonate; In methanol; N,N-dimethyl-formamide;
DOI:10.1021/jm00062a005