6-(8-(benzo[d]thiazol-2-ylcarbamoyl)-3,4-dihydroisoquinolin-2(1H)-yl)-3-(3-(4-(4-methylpiperazine-1-carbonyl)phenoxy)propyl)picolinic acid

Base Information

Chemical Name:6-(8-(benzo[d]thiazol-2-ylcarbamoyl)-3,4-dihydroisoquinolin-2(1H)-yl)-3-(3-(4-(4-methylpiperazine-1-carbonyl)phenoxy)propyl)picolinic acid
CAS No.:1235034-24-8
Molecular Formula:C₃₈H₃₈N₆O₅S
Molecular Weight:690.823
Hs Code.:

Synonyms:6-(8-(benzo[d]thiazol-2-ylcarbamoyl)-3,4-dihydroisoquinolin-2(1H)-yl)-3-(3-(4-(4-methylpiperazine-1-carbonyl)phenoxy)propyl)picolinic acid

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Chemical Property of 6-(8-(benzo[d]thiazol-2-ylcarbamoyl)-3,4-dihydroisoquinolin-2(1H)-yl)-3-(3-(4-(4-methylpiperazine-1-carbonyl)phenoxy)propyl)picolinic acid

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Technology Process of 6-(8-(benzo[d]thiazol-2-ylcarbamoyl)-3,4-dihydroisoquinolin-2(1H)-yl)-3-(3-(4-(4-methylpiperazine-1-carbonyl)phenoxy)propyl)picolinic acid

There total 1 articles about 6-(8-(benzo[d]thiazol-2-ylcarbamoyl)-3,4-dihydroisoquinolin-2(1H)-yl)-3-(3-(4-(4-methylpiperazine-1-carbonyl)phenoxy)propyl)picolinic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

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Reference yield:

: 1235036-21-1
(Z)-tert-butyl 3-(3-hydroxypropyl)-6-(8-(3-((2-(trimethylsilyl)ethoxy)methyl)benzo[d]thiazol-2(3H)-ylidenecarbamoyl)-3,4-dihydroisoquinolin-2(lH)-yl)picolinate

: 85858-94-2
1-(4-hydroxybenzoyl)-4-methyl-piperazine

: 1235034-24-8
6-(8-(benzo[d]thiazol-2-ylcarbamoyl)-3,4-dihydroisoquinolin-2(1H)-yl)-3-(3-(4-(4-methylpiperazine-1-carbonyl)phenoxy)propyl)picolinic acid

Guidance literature:: (Z)-tert-butyl 3-(3-hydroxypropyl)-6-(8-(3-((2-(trimethylsilyl)ethoxy)methyl)benzo[d]thiazol-2(3H)-ylidenecarbamoyl)-3,4-dihydroisoquinolin-2(lH)-yl)picolinate; With 1H-imidazole; iodine; triphenylphosphine; In diethyl ether; acetonitrile; at 20 ℃; for 0.75h;

1-(4-hydroxybenzoyl)-4-methyl-piperazine; With sodium hydride; In N,N-dimethyl-formamide; for 3h;

With triethylsilane; trifluoroacetic acid; In dichloromethane; at 20 ℃; for 5h;