(R,S)-3,4-dibromo-N-[[4-(3,4-dihydro-2(1H)-oxoquinazolin-3-yl)-1-piperidinyl]-carbonyl]-phenylalanine ethyl ester

Base Information

Chemical Name:(R,S)-3,4-dibromo-N-[[4-(3,4-dihydro-2(1H)-oxoquinazolin-3-yl)-1-piperidinyl]-carbonyl]-phenylalanine ethyl ester
CAS No.:726184-73-2
Molecular Formula:C₂₅H₂₈Br₂N₄O₄
Molecular Weight:608.33
Hs Code.:

Synonyms:(R,S)-3,4-dibromo-N-[[4-(3,4-dihydro-2(1H)-oxoquinazolin-3-yl)-1-piperidinyl]-carbonyl]-phenylalanine ethyl ester

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Chemical Property of (R,S)-3,4-dibromo-N-[[4-(3,4-dihydro-2(1H)-oxoquinazolin-3-yl)-1-piperidinyl]-carbonyl]-phenylalanine ethyl ester

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Technology Process of (R,S)-3,4-dibromo-N-[[4-(3,4-dihydro-2(1H)-oxoquinazolin-3-yl)-1-piperidinyl]-carbonyl]-phenylalanine ethyl ester

There total 1 articles about (R,S)-3,4-dibromo-N-[[4-(3,4-dihydro-2(1H)-oxoquinazolin-3-yl)-1-piperidinyl]-carbonyl]-phenylalanine ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 64.0%

: 79098-75-2
3-piperidin-4-yl-3,4-dihydro-1H-quinazoline-2-one

: 726184-73-2
(R,S)-3,4-dibromo-N-[[4-(3,4-dihydro-2(1H)-oxoquinazolin-3-yl)-1-piperidinyl]-carbonyl]-phenylalanine ethyl ester

Guidance literature:: ethyl-2-amino-3-(3,4-dibromo-phenyl)-propionate; With 1,1'-Carbonyl-di-(1,2,4-triazole); In tetrahydrofuran; at 0 - 20 ℃; for 2h;

3-piperidin-4-yl-3,4-dihydro-1H-quinazoline-2-one; In tetrahydrofuran; at 20 ℃; Heating / reflux;

Reference yield: 52.0%

: 726184-73-2
(R,S)-3,4-dibromo-N-[[4-(3,4-dihydro-2(1H)-oxoquinazolin-3-yl)-1-piperidinyl]-carbonyl]-phenylalanine ethyl ester

: 726184-74-3
(R,S)-3,4-dibromo-N-[[4-(3,4-dihydro-2(1H)-oxoquinazolin-3-yl)-1-piperidinyl]-carbonyl]-phenylalanine

Guidance literature:: (R,S)-3,4-dibromo-N-[[4-(3,4-dihydro-2(1H)-oxoquinazolin-3-yl)-1-piperidinyl]-carbonyl]-phenylalanine ethyl ester; With sodium hydroxide; In ethanol; water; at 20 ℃; for 3.5h;

With hydrogenchloride; In water;