3-(Piperidin-4-YL)-3,4-dihydroquinazolin-2(1H)-one

Base Information

Chemical Name:3-(Piperidin-4-YL)-3,4-dihydroquinazolin-2(1H)-one
CAS No.:79098-75-2
Molecular Formula:C13H17N3O
Molecular Weight:231.297
Hs Code.:2933990090
DSSTox Substance ID:DTXSID50453067
Wikidata:Q72500682
Mol file:79098-75-2.mol

Synonyms:79098-75-2;3-(PIPERIDIN-4-YL)-3,4-DIHYDROQUINAZOLIN-2(1H)-ONE;3-Piperidin-4-yl-3,4-dihydro-1H-quinazolin-2-one;3-(4-piperidinyl)-3,4-dihydro-2(1H)-quinazolinone;3-piperidin-4-yl-1,4-dihydroquinazolin-2-one;2(1H)-Quinazolinone, 3,4-dihydro-3-(4-piperidinyl)-;3,4-DIHYDRO-3-(4-PIPERIDINYL)-2(1H)-QUINAZOLINONE;3-Piperidin-4-yl-3,4-dihydro-quinazolin-2-ol;SCHEMBL2100919;DTXSID50453067;KSTFHYBYFDYWSD-UHFFFAOYSA-N;CS-M1905;MFCD11043062;AKOS005073804;SB43270;SS-3104;AM101288;FT-0681849;A24784;3-(piperidine-4-yl)-1,4-dihydroquinazoline-2-on;3-piperidin-4-yl-3,4dihydro-1H-quinazolin-2-one;3-piperidin-4yl-3,4-dihydro-1H-quinazolin-2one;A839581;3-piperidin-4-yl-3,4-dihydroquinazolin-2(1H)-one;J-510938;2(1H)-Quinazolinone,3,4-dihydro-3-(4-piperidinyl)-;3,4-dihydro-3-(piperidin-4-yl)quinazolin-2(1H)-one;4-(2-Oxo-1,4-dihydro-2H-quinazolin-3-yl)piperidine;3-(Piperidin-4-yl)-3,4- dihydroquinazolin-2(1H)-one;4-(2-Oxo-1,4-dihydro-2H-quinazolin-3-yl) piperidine;3-(Piperidin-4-yl)-1,2,3,4-tetrahydroquinazolin-2-one;3-(4-piperidyl)-1,4-dihydroquinazolin-2-one

Suppliers and Price of 3-(Piperidin-4-YL)-3,4-dihydroquinazolin-2(1H)-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
3-(Piperidin-4-yl)-3,4-dihydroquinazolin-2(1H)-one
10mg
$ 45.00

SynQuest Laboratories
3-(Piperidin-4-yl)-1,2,3,4-tetrahydroquinazolin-2-one
5 g
$ 1479.00

Matrix Scientific
3-(4-Piperidinyl)-3,4-dihydro-2(1H)-quinazolinone >95%
1g
$ 440.00

Matrix Scientific
3-(4-Piperidinyl)-3,4-dihydro-2(1H)-quinazolinone >95%
500mg
$ 325.00

Matrix Scientific
3-(4-Piperidinyl)-3,4-dihydro-2(1H)-quinazolinone >95%
5g
$ 1200.00

Crysdot
3-Piperidin-4-yl-3,4-dihydro-1H-quinazolin-2-one 95+%
5g
$ 970.00

Crysdot
3-Piperidin-4-yl-3,4-dihydro-1H-quinazolin-2-one 95+%
1g
$ 324.00

Chemenu
3-(piperidin-4-yl)-3,4-dihydroquinazolin-2(1H)-one 95%
1g
$ 306.00

Chemenu
3-(piperidin-4-yl)-3,4-dihydroquinazolin-2(1H)-one 95%
5g
$ 916.00

Chemcia Scientific
3-Piperidin-4-yl-3,4-dihydro-1H-quinazolin-2-one ＞95%
5 G
$ 675.00

Total 22 raw suppliers

Chemical Property of 3-(Piperidin-4-YL)-3,4-dihydroquinazolin-2(1H)-one

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Refractive Index:1.581
Boiling Point:459.008 °C at 760 mmHg
PKA:14.85±0.20(Predicted)
Flash Point:231.4 °C
PSA：44.37000
Density:1.18 g/cm³
LogP:2.19080
Storage Temp.:Keep in dark place,Inert atmosphere,Room temperature
XLogP3:0.8
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:231.137162174
Heavy Atom Count:17
Complexity:288

Purity/Quality:

97% ^*data from raw suppliers

3-(Piperidin-4-yl)-3,4-dihydroquinazolin-2(1H)-one ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CNCCC1N2CC3=CC=CC=C3NC2=O

Technology Process of 3-(Piperidin-4-YL)-3,4-dihydroquinazolin-2(1H)-one

There total 14 articles about 3-(Piperidin-4-YL)-3,4-dihydroquinazolin-2(1H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 79098-88-7
1-benzyl-4-(1,2,3,4-tetrahydro-2-oxo-3-quinazolinyl)piperidine

: 79098-75-2
3-piperidin-4-yl-3,4-dihydro-1H-quinazoline-2-one

Guidance literature:: With palladium 10% on activated carbon; hydrogen; In methanol; for 48h;

Reference yield: 92.0%

: 960221-97-0
tert-butyl 4-(2-oxo-1,2,3,4-tetrahydroquinazolin-3-yl)piperidine-1-carboxylate

: 79098-75-2
3-piperidin-4-yl-3,4-dihydro-1H-quinazoline-2-one

Guidance literature:: With trifluoroacetic acid; In dichloromethane; at 20 ℃;
DOI:10.1016/j.tetlet.2018.08.002

Reference yield:

: 79099-03-9
2-amino-N-[1-(phenylmethyl)-4-piperidinyl]-benzenemethanamine

: 530-62-1
1,1'-carbonyldiimidazole

: 79098-75-2
3-piperidin-4-yl-3,4-dihydro-1H-quinazoline-2-one

Guidance literature:: 2-amino-N-[1-(phenylmethyl)-4-piperidinyl]-benzenemethanamine; 1,1'-carbonyldiimidazole; In acetonitrile; Reflux;

With hydrogen; palladium(II) hydroxide; In methanol;