1-[6-(4-bromo-2-chlorophenyl)-5-(4-chlorophenyl)-3-(hydroxymethyl)furo[2,3-b]pyridin-2-yl]-2,2-dimethylpropan-1-one

Base Information

Chemical Name:1-[6-(4-bromo-2-chlorophenyl)-5-(4-chlorophenyl)-3-(hydroxymethyl)furo[2,3-b]pyridin-2-yl]-2,2-dimethylpropan-1-one
CAS No.:1072708-46-3
Molecular Formula:C₂₅H₂₀BrCl₂NO₃
Molecular Weight:533.249
Hs Code.:

Synonyms:1-[6-(4-bromo-2-chlorophenyl)-5-(4-chlorophenyl)-3-(hydroxymethyl)furo[2,3-b]pyridin-2-yl]-2,2-dimethylpropan-1-one

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Chemical Property of 1-[6-(4-bromo-2-chlorophenyl)-5-(4-chlorophenyl)-3-(hydroxymethyl)furo[2,3-b]pyridin-2-yl]-2,2-dimethylpropan-1-one

Chemical Property:

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Technology Process of 1-[6-(4-bromo-2-chlorophenyl)-5-(4-chlorophenyl)-3-(hydroxymethyl)furo[2,3-b]pyridin-2-yl]-2,2-dimethylpropan-1-one

There total 2 articles about 1-[6-(4-bromo-2-chlorophenyl)-5-(4-chlorophenyl)-3-(hydroxymethyl)furo[2,3-b]pyridin-2-yl]-2,2-dimethylpropan-1-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1072708-39-4
1-[6-(4-Bromo-2-chlorophenyl)-3-(bromomethyl)-5-(4-chlorophenyl)furo[2,3-b]pyridin-2-yl]-2,2-dimethylpropan-1-one

: 1072708-46-3
1-[6-(4-bromo-2-chlorophenyl)-5-(4-chlorophenyl)-3-(hydroxymethyl)furo[2,3-b]pyridin-2-yl]-2,2-dimethylpropan-1-one

: 1072708-41-8
6-(4-Bromo-2-chlorophenyl)-5-(4-chlorophenyl)-2-(2,2-dimethylpropanoyl)furo[2,3-b]pyridine-3-carboxylic acid

Guidance literature:: With acetic acid; sodium nitrite; In dimethyl sulfoxide; at 20 - 40 ℃;

Reference yield:

: 1072708-39-4
1-[6-(4-Bromo-2-chlorophenyl)-3-(bromomethyl)-5-(4-chlorophenyl)furo[2,3-b]pyridin-2-yl]-2,2-dimethylpropan-1-one

: 108-18-9
diisopropylamine

: 1072708-46-3
1-[6-(4-bromo-2-chlorophenyl)-5-(4-chlorophenyl)-3-(hydroxymethyl)furo[2,3-b]pyridin-2-yl]-2,2-dimethylpropan-1-one

: 1072708-44-1
6-(4-bromo-2-chlorophenyl)-5-(4-chlorophenyl)-2-(2,2-dimethylpropanoyl)furo[2,3-b]pyridine-3-carboxylic acid diisopropylamine salt

Guidance literature:: 1-[6-(4-Bromo-2-chlorophenyl)-3-(bromomethyl)-5-(4-chlorophenyl)furo[2,3-b]pyridin-2-yl]-2,2-dimethylpropan-1-one; With aminosulfonic acid; In water; acetone; at 20 ℃; for 0.333333h;

With sodium chlorite; In water; acetone; at 25 - 30 ℃; for 0.916667h;

diisopropylamine; In ethyl acetate; at 20 ℃; for 2h;