6-(4-bromo-2-chlorophenyl)-5-(4-chlorophenyl)-2-(2,2-dimethylpropanoyl)furo[2,3-b]pyridine-3-carboxylic acid diisopropylamine salt

Base Information

Chemical Name:6-(4-bromo-2-chlorophenyl)-5-(4-chlorophenyl)-2-(2,2-dimethylpropanoyl)furo[2,3-b]pyridine-3-carboxylic acid diisopropylamine salt
CAS No.:1072708-44-1
Molecular Formula:C₆H₁₅N*C₂₅H₁₈BrCl₂NO₄
Molecular Weight:648.424
Hs Code.:

Synonyms:6-(4-bromo-2-chlorophenyl)-5-(4-chlorophenyl)-2-(2,2-dimethylpropanoyl)furo[2,3-b]pyridine-3-carboxylic acid diisopropylamine salt

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Chemical Property of 6-(4-bromo-2-chlorophenyl)-5-(4-chlorophenyl)-2-(2,2-dimethylpropanoyl)furo[2,3-b]pyridine-3-carboxylic acid diisopropylamine salt

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Technology Process of 6-(4-bromo-2-chlorophenyl)-5-(4-chlorophenyl)-2-(2,2-dimethylpropanoyl)furo[2,3-b]pyridine-3-carboxylic acid diisopropylamine salt

There total 1 articles about 6-(4-bromo-2-chlorophenyl)-5-(4-chlorophenyl)-2-(2,2-dimethylpropanoyl)furo[2,3-b]pyridine-3-carboxylic acid diisopropylamine salt which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1072708-39-4
1-[6-(4-Bromo-2-chlorophenyl)-3-(bromomethyl)-5-(4-chlorophenyl)furo[2,3-b]pyridin-2-yl]-2,2-dimethylpropan-1-one

: 108-18-9
diisopropylamine

: 1072708-46-3
1-[6-(4-bromo-2-chlorophenyl)-5-(4-chlorophenyl)-3-(hydroxymethyl)furo[2,3-b]pyridin-2-yl]-2,2-dimethylpropan-1-one

: 1072708-44-1
6-(4-bromo-2-chlorophenyl)-5-(4-chlorophenyl)-2-(2,2-dimethylpropanoyl)furo[2,3-b]pyridine-3-carboxylic acid diisopropylamine salt

Guidance literature:: 1-[6-(4-Bromo-2-chlorophenyl)-3-(bromomethyl)-5-(4-chlorophenyl)furo[2,3-b]pyridin-2-yl]-2,2-dimethylpropan-1-one; With aminosulfonic acid; In water; acetone; at 20 ℃; for 0.333333h;

With sodium chlorite; In water; acetone; at 25 - 30 ℃; for 0.916667h;

diisopropylamine; In ethyl acetate; at 20 ℃; for 2h;

Reference yield:

: 1072708-44-1
6-(4-bromo-2-chlorophenyl)-5-(4-chlorophenyl)-2-(2,2-dimethylpropanoyl)furo[2,3-b]pyridine-3-carboxylic acid diisopropylamine salt

: 1072708-49-6
6-(4-Bromo-2-chlorophenyl)-5-(4-chlorophenyl)-2-(2,2-dimethylpropanoyl)furo[2,3-b]pyridine-3-carboxamide

Guidance literature:: 6-(4-bromo-2-chlorophenyl)-5-(4-chlorophenyl)-2-(2,2-dimethylpropanoyl)furo[2,3-b]pyridine-3-carboxylic acid diisopropylamine salt; With oxalyl dichloride; N,N-dimethyl-formamide; In ethyl acetate; at 20 - 25 ℃; for 0.583333 - 1.08333h;

With ammonia; In n-heptane; water; ethyl acetate; at -30 - 20 ℃; for 2.5h; Product distribution / selectivity;

Reference yield:

: 1072708-44-1
6-(4-bromo-2-chlorophenyl)-5-(4-chlorophenyl)-2-(2,2-dimethylpropanoyl)furo[2,3-b]pyridine-3-carboxylic acid diisopropylamine salt

: 74-89-5
methylamine

: 1072708-37-2
6-(4-Bromo-2-chlorophenyl)-5-(4-chlorophenyl)-2-(2,2-dimethylpropanoyl)-N-methylfuro[2,3-b]pyridine-3-carboxamide

Guidance literature:: With benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; benzotriazol-1-ol; In tetrahydrofuran; N,N-dimethyl-formamide; at 20 ℃; for 0.25h; Product distribution / selectivity;