methyl 3α-(4-tert-butoxycarbonylaminophenylaminocarbonyl)amino-7α,12α-bis[(phenylaminocarbonyl)amino]-5β-cholan-24-oate

Base Information

Chemical Name:methyl 3α-(4-tert-butoxycarbonylaminophenylaminocarbonyl)amino-7α,12α-bis[(phenylaminocarbonyl)amino]-5β-cholan-24-oate
CAS No.:1352749-33-7
Molecular Formula:C₅₁H₆₉N₇O₇
Molecular Weight:892.152
Hs Code.:

Synonyms:methyl 3α-(4-tert-butoxycarbonylaminophenylaminocarbonyl)amino-7α,12α-bis[(phenylaminocarbonyl)amino]-5β-cholan-24-oate

Suppliers and Price of methyl 3α-(4-tert-butoxycarbonylaminophenylaminocarbonyl)amino-7α,12α-bis[(phenylaminocarbonyl)amino]-5β-cholan-24-oate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of methyl 3α-(4-tert-butoxycarbonylaminophenylaminocarbonyl)amino-7α,12α-bis[(phenylaminocarbonyl)amino]-5β-cholan-24-oate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of methyl 3α-(4-tert-butoxycarbonylaminophenylaminocarbonyl)amino-7α,12α-bis[(phenylaminocarbonyl)amino]-5β-cholan-24-oate

There total 4 articles about methyl 3α-(4-tert-butoxycarbonylaminophenylaminocarbonyl)amino-7α,12α-bis[(phenylaminocarbonyl)amino]-5β-cholan-24-oate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 862202-69-5
methyl 3α-amino-7α,12α-bis[(phenylaminocarbonyl)amino]-5β-cholan-24-oate

: 300583-02-2
4-tert-butoxycarbonylaminophenylisocyanate

: 1352749-33-7
methyl 3α-(4-tert-butoxycarbonylaminophenylaminocarbonyl)amino-7α,12α-bis[(phenylaminocarbonyl)amino]-5β-cholan-24-oate

Guidance literature:: With dmap; N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; at 70 ℃; for 2h; Inert atmosphere;
DOI:10.1002/anie.201105216

Reference yield:

: tert-butyl (4-(azidocarbonyl)phenyl)carbamate

: 1352749-33-7
methyl 3α-(4-tert-butoxycarbonylaminophenylaminocarbonyl)amino-7α,12α-bis[(phenylaminocarbonyl)amino]-5β-cholan-24-oate

Guidance literature:: Multi-step reaction with 2 steps

1: toluene / 2 h / Reflux; Inert atmosphere

2: dmap; N-ethyl-N,N-diisopropylamine / tetrahydrofuran / 2 h / 70 °C / Inert atmosphere

With dmap; N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; toluene;
DOI:10.1002/anie.201105216

Reference yield:

: C₁₅H₁₉NO₆

: 1352749-33-7
methyl 3α-(4-tert-butoxycarbonylaminophenylaminocarbonyl)amino-7α,12α-bis[(phenylaminocarbonyl)amino]-5β-cholan-24-oate

Guidance literature:: Multi-step reaction with 3 steps

1: sodium azide / tetrahydrofuran; water / 1 h / Inert atmosphere

2: toluene / 2 h / Reflux; Inert atmosphere

3: dmap; N-ethyl-N,N-diisopropylamine / tetrahydrofuran / 2 h / 70 °C / Inert atmosphere

With dmap; sodium azide; N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; water; toluene;
DOI:10.1002/anie.201105216