benzyl 4-(2-{[4-(1-methyl-1H-tetrazol-5-yl)phenyl]sulfonyl}ethyl)-piperidine-1-carboxylate

Base Information

Chemical Name:benzyl 4-(2-{[4-(1-methyl-1H-tetrazol-5-yl)phenyl]sulfonyl}ethyl)-piperidine-1-carboxylate
CAS No.:718611-03-1
Molecular Formula:C₂₃H₂₇N₅O₄S
Molecular Weight:469.564
Hs Code.:

Synonyms:benzyl 4-(2-{[4-(1-methyl-1H-tetrazol-5-yl)phenyl]sulfonyl}ethyl)-piperidine-1-carboxylate

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Chemical Property of benzyl 4-(2-{[4-(1-methyl-1H-tetrazol-5-yl)phenyl]sulfonyl}ethyl)-piperidine-1-carboxylate

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Technology Process of benzyl 4-(2-{[4-(1-methyl-1H-tetrazol-5-yl)phenyl]sulfonyl}ethyl)-piperidine-1-carboxylate

There total 3 articles about benzyl 4-(2-{[4-(1-methyl-1H-tetrazol-5-yl)phenyl]sulfonyl}ethyl)-piperidine-1-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 718611-01-9
benzyl 4-(2-{[4-(1H-tetrazol-5-yl)phenyl]sulfonyl}ethyl)piperidine-1-carboxylate

: 74-88-4
methyl iodide

: 718611-03-1
benzyl 4-(2-{[4-(1-methyl-1H-tetrazol-5-yl)phenyl]sulfonyl}ethyl)-piperidine-1-carboxylate

: 718611-02-0
benzyl 4-(2-{[4-(2-methyl-2H-tetrazol-5-yl)phenyl]sulfonyl}ethyl)-piperidine-1-carboxylate

Guidance literature:: With sodium hydroxide; In ethanol; for 88h;

Reference yield:

: 4-[(2-piperidin-4-ylethyl)sulfonyl]benzonitrile

: 718611-03-1
benzyl 4-(2-{[4-(1-methyl-1H-tetrazol-5-yl)phenyl]sulfonyl}ethyl)-piperidine-1-carboxylate

Guidance literature:: Multi-step reaction with 3 steps

1: triethylamine / dichloromethane / 2 h / 0 - 20 °C

2: sodium azide; ammonium chloride / DMF (N,N-dimethyl-formamide) / 4 h / 100 °C

3: sodium hydroxide / ethanol / 88 h

With sodium hydroxide; sodium azide; ammonium chloride; triethylamine; In DMF (N,N-dimethyl-formamide); ethanol; dichloromethane;

Reference yield:

: 501-53-1,94274-21-2
benzyl chloroformate

: 718611-03-1
benzyl 4-(2-{[4-(1-methyl-1H-tetrazol-5-yl)phenyl]sulfonyl}ethyl)-piperidine-1-carboxylate

Guidance literature:: Multi-step reaction with 3 steps

1: triethylamine / dichloromethane / 2 h / 0 - 20 °C

2: sodium azide; ammonium chloride / DMF (N,N-dimethyl-formamide) / 4 h / 100 °C

3: sodium hydroxide / ethanol / 88 h

With sodium hydroxide; sodium azide; ammonium chloride; triethylamine; In DMF (N,N-dimethyl-formamide); ethanol; dichloromethane;