3,4-DI-O-ACETYL-6-O-(TERT-BUTYLDIMETHYLSILYL)-D-GLUCAL

Base Information

Chemical Name:3,4-DI-O-ACETYL-6-O-(TERT-BUTYLDIMETHYLSILYL)-D-GLUCAL
CAS No.:117136-33-1
Molecular Formula:C₁₆H₂₈O₆Si
Molecular Weight:344.48
Hs Code.:
Mol file:117136-33-1.mol

Synonyms:D-arabino-Hex-1-enitol,1,5-anhydro-2-deoxy-6-O-[(1,1-dimethylethyl)dimethylsilyl]-, diacetate (9CI)

Suppliers and Price of 3,4-DI-O-ACETYL-6-O-(TERT-BUTYLDIMETHYLSILYL)-D-GLUCAL

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Sigma-Aldrich
3,4-Di-O-acetyl-6-O-(tert-butyldimethylsilyl)-D-glucal 96%
100mg
$ 109.00

Crysdot
(2R,3S,4R)-2-(((tert-Butyldimethylsilyl)oxy)methyl)-3,4-dihydro-2H-pyran-3,4-diyldiacetate 95+%
5g
$ 668.00

Chemenu
(2R,3S,4R)-2-(((tert-Butyldimethylsilyl)oxy)methyl)-3,4-dihydro-2H-pyran-3,4-diyldiacetate 95%
5g
$ 631.00

American Custom Chemicals Corporation
3,4-DI-O-ACETYL-6-O-(TERT-BUTYLDIMETHYLSILYL)-D-GLUCAL 95.00%
100MG
$ 643.85

Alfa Aesar
3,4-Di-O-acetyl-6-O-tert-butyldimethylsilyl-D-glucal, 97%
1g
$ 130.00

Alfa Aesar
3,4-Di-O-acetyl-6-O-tert-butyldimethylsilyl-D-glucal, 97%
250mg
$ 43.70

Total 5 raw suppliers

Chemical Property of 3,4-DI-O-ACETYL-6-O-(TERT-BUTYLDIMETHYLSILYL)-D-GLUCAL

Chemical Property:

Refractive Index:n20/D 1.456(lit.)
Flash Point:>230 °F
PSA：71.06000
Density:1.044 g/mL at 25 °C(lit.)
LogP:2.78410
Storage Temp.:?20°C

Purity/Quality:

95% ^*data from raw suppliers

3,4-Di-O-acetyl-6-O-(tert-butyldimethylsilyl)-D-glucal 96% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses Important building block for both solution- and solid-phase synthesis of oligosaccharides.1

Technology Process of 3,4-DI-O-ACETYL-6-O-(TERT-BUTYLDIMETHYLSILYL)-D-GLUCAL

There total 8 articles about 3,4-DI-O-ACETYL-6-O-(TERT-BUTYLDIMETHYLSILYL)-D-GLUCAL which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 58871-09-3
6-O-tert-butyldimethylsilyl-D-glucal

: 108-24-7
acetic anhydride

: 136656-49-0,117136-33-1
3,4-di-O-acetyl-1,5-anhydro-6-O-t-butyldimethylsilyl-2-deoxy-D-arabino-hex-1-enitol

Guidance literature:: With dmap; triethylamine; In dichloromethane; at 23 ℃; for 2h;
DOI:10.1002/(SICI)1521-3773(19990115)38:1/2<240::AID-ANIE240>3.0.CO;2-5

Reference yield: 90.0%

: 82295-98-5
3,4-di-O-acetyl-1,5-anhydro-2-deoxy-D-arabino-hex-1-enitol

: 18162-48-6
tert-butyldimethylsilyl chloride

: 136656-49-0,117136-33-1
3,4-di-O-acetyl-1,5-anhydro-6-O-t-butyldimethylsilyl-2-deoxy-D-arabino-hex-1-enitol

Guidance literature:: With 1H-imidazole; In N,N-dimethyl-formamide;
DOI:10.1021/acschembio.0c00409

Reference yield:

: 18162-48-6
tert-butyldimethylsilyl chloride

: 136656-49-0,117136-33-1
3,4-di-O-acetyl-1,5-anhydro-6-O-t-butyldimethylsilyl-2-deoxy-D-arabino-hex-1-enitol

Guidance literature:: Multi-step reaction with 2 steps

1: 82 percent / imidazole / dimethylformamide / 1 h / 0 - 23 °C

2: 97 percent / Et₃N, DMAP / CH₂Cl₂ / 2 h / 23 °C

With 1H-imidazole; dmap; triethylamine; In dichloromethane; N,N-dimethyl-formamide;
DOI:10.1002/(SICI)1521-3773(19990115)38:1/2<240::AID-ANIE240>3.0.CO;2-5