(E)-1,2-dimethoxy-4-[2-(4-methylbenzene)sulfonylvinyl]benzene

Base Information

• Chemical Name: (E)-1,2-dimethoxy-4-[2-(4-methylbenzene)sulfonylvinyl]benzene
• CAS No.: 56759-21-8
• Molecular Formula: C₁₇H₁₈O₄S
• Molecular Weight: 318.394
• Mol file: 56759-21-8.mol

Synonyms:(E)-1,2-dimethoxy-4-[2-(4-methylbenzene)sulfonylvinyl]benzene

Chemical Property of (E)-1,2-dimethoxy-4-[2-(4-methylbenzene)sulfonylvinyl]benzene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of (E)-1,2-dimethoxy-4-[2-(4-methylbenzene)sulfonylvinyl]benzene

There total 3 articles about (E)-1,2-dimethoxy-4-[2-(4-methylbenzene)sulfonylvinyl]benzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

3,4-dimethoxyphenylacetaldehyde (5703-21-9) + sodium 4-methylbenzenesulfinate (824-79-3) → (E)-1,2-dimethoxy-4-[2-(4-methylbenzene)sulfonylvinyl]benzene (56759-21-8)

Guidance literature:

3,4-dimethoxyphenylacetaldehyde; With acetic anhydride; In neat (no solvent); at 25 ℃; for 0.166667h;

sodium 4-methylbenzenesulfinate; In neat (no solvent); at 25 ℃; for 4h; Reagent/catalyst; Solvent; Temperature; stereoselective reaction;

DOI:10.1055/s-0037-1610822

Reference yield: 80.0%

4-ethynylveratrole (4302-52-7) + sodium 4-methylbenzenesulfinate (824-79-3) → (E)-1,2-dimethoxy-4-[2-(4-methylbenzene)sulfonylvinyl]benzene (56759-21-8)

Guidance literature:

With graphenit-Cu(I); Amberlyst 15; In ethanol; dimethyl sulfoxide; at 100 ℃; for 4h; stereoselective reaction;

DOI:10.1002/asia.201900781

Reference yield:

→ (E)-1,2-dimethoxy-4-[2-(4-methylbenzene)sulfonylvinyl]benzene (56759-21-8)

Guidance literature:

/BRN= 473899/, /BRN= 331311/, Benzylamin (als Katalys.);

upstream raw materials:

3,4-dimethoxyphenylacetaldehyde

sodium 4-methylbenzenesulfinate

4-ethynylveratrole

Downstream raw materials:

1,2-Dimethoxy-4-[(1S,2R)-2-(toluene-4-sulfonyl)-cyclopropyl]-benzene