1-(6-fluoro-1H-indol-3-yl)ethan-1-one

Base Information

Chemical Name:1-(6-fluoro-1H-indol-3-yl)ethan-1-one
CAS No.:949035-26-1
Molecular Formula:C₁₀H₈FNO
Molecular Weight:177.178
Hs Code.:
DSSTox Substance ID:DTXSID201297937

Synonyms:949035-26-1;1-(6-fluoro-1H-indol-3-yl)ethan-1-one;1-(6-fluoro-1H-indol-3-yl)ethanone;3-Acetyl-6-fluoroindole;DTXSID201297937;MFCD11105939;AKOS009343504;NCGC00321882-01;SY181879;CS-0252967;EN300-62134;C91184;AB01318092-02;1-(6-Fluoro-1H-indol-3-yl)ethanone, AldrichCPR;Z234897299

Suppliers and Price of 1-(6-fluoro-1H-indol-3-yl)ethan-1-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 2 raw suppliers

Chemical Property of 1-(6-fluoro-1H-indol-3-yl)ethan-1-one

Chemical Property:

XLogP3:2.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:177.058992041
Heavy Atom Count:13
Complexity:219

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(=O)C1=CNC2=C1C=CC(=C2)F

Technology Process of 1-(6-fluoro-1H-indol-3-yl)ethan-1-one

There total 1 articles about 1-(6-fluoro-1H-indol-3-yl)ethan-1-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 56.0%

: 399-51-9
6-fluoro-1H-indole

: 75-36-5
acetyl chloride

: 949035-26-1
1-(6-fluoro-1H-indol-3-yl)ethan-1-one

Guidance literature:: 6-fluoro-1H-indole; With tin(IV) chloride; In dichloromethane; at 0 - 20 ℃; for 0.5h; Inert atmosphere;

acetyl chloride; In nitromethane; dichloromethane; for 4h; Inert atmosphere;

Reference yield: 67.0%

: 949035-26-1
1-(6-fluoro-1H-indol-3-yl)ethan-1-one

: 619-44-3
methyl 4-iodobenzoate

: C₁₈H₁₄FNO₃

Guidance literature:: With palladium diacetate; silver trifluoroacetate; toluene-4-sulfonic acid; In water; at 60 ℃; for 0.666667h; regioselective reaction;
DOI:10.1039/d0sc05409g

Reference yield: 56.0%

: 949035-26-1
1-(6-fluoro-1H-indol-3-yl)ethan-1-one

: 619-44-3
methyl 4-iodobenzoate

: C₁₈H₁₄FNO₃

Guidance literature:: With palladium diacetate; silver trifluoroacetate; trifluoroacetic acid; at 100 ℃; for 24h; regioselective reaction;
DOI:10.1039/d0sc05409g