C₂₄H₂₈ClNO₆

Base Information

• Chemical Name: C₂₄H₂₈ClNO₆
• CAS No.: 1239897-04-1
• Molecular Formula: C₂₄H₂₈ClNO₆
• Molecular Weight: 461.942
• Mol file: 1239897-04-1.mol

Synonyms:C₂₄H₂₈ClNO₆

Chemical Property of C₂₄H₂₈ClNO₆

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₄H₂₈ClNO₆

There total 2 articles about C₂₄H₂₈ClNO₆ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-(2-chloroethyl)-4-methyleneoxetan-2-one → C24H28ClNO6 (1239897-04-1)

Guidance literature:

Multi-step reaction with 2 steps

1.1: 2-hydroxypyridin / 1,2-dichloro-ethane / 23 - 48 °C / Microwave irradiation; Inert atmosphere

2.1: morpholine; tetrakis(triphenylphosphine) palladium⁽⁰⁾ / tetrahydrofuran / 1.17 h / -5 °C / Inert atmosphere

2.2: pH Ca_. 3 / Inert atmosphere

With morpholine; 2-hydroxypyridin; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In tetrahydrofuran; 1,2-dichloro-ethane;

DOI:10.1021/jo101638r

Reference yield:

C27H32ClNO6 (1239897-09-6) → C24H28ClNO6 (1239897-04-1)

Guidance literature:

Multi-step reaction with 2 steps

1.1: toluene-4-sulfonic acid / methanol; ethyl acetate / 8 h / 45 °C / Inert atmosphere

2.1: morpholine; tetrakis(triphenylphosphine) palladium⁽⁰⁾ / tetrahydrofuran / 1.17 h / -5 °C / Inert atmosphere

2.2: pH Ca_. 3 / Inert atmosphere

With morpholine; tetrakis(triphenylphosphine) palladium⁽⁰⁾; toluene-4-sulfonic acid; In tetrahydrofuran; methanol; ethyl acetate;

DOI:10.1021/jo101638r

Reference yield:

C24H28ClNO6 (1239897-04-1) → 1-(benzyloxymethyl)-4-(2-chloroethyl)-2-(4-methoxybenzyl)-5-methyl-6-oxa-2-azabicyclo[3.2.0]heptane-3,7-dione (1127249-86-8) + C24H26ClNO5

Guidance literature:

With 4-pyrrolidin-1-ylpyridine; methanesulfonyl chloride; In toluene; at -10 - -5 ℃; for 1.5h; optical yield given as %ee; Inert atmosphere;

DOI:10.1039/c0cc00607f

upstream raw materials:

C₂₇H₃₂ClNO₆

Downstream raw materials:

1-(benzyloxymethyl)-4-(2-chloroethyl)-2-(4-methoxybenzyl)-5-methyl-6-oxa-2-azabicyclo[3.2.0]heptane-3,7-dione

C₂₄H₂₆ClNO₅