N²-tert-butoxycarbonyle-4-iso-propyl-N⁵-benzyl-1,2,5-thiadiazolidine 1,2-dioxyde

Base Information

• Chemical Name: N²-tert-butoxycarbonyle-4-iso-propyl-N⁵-benzyl-1,2,5-thiadiazolidine 1,2-dioxyde
• CAS No.: 263719-81-9
• Molecular Formula: C₁₇H₂₆N₂O₄S
• Molecular Weight: 354.47
• Mol file: 263719-81-9.mol

Synonyms:N²-tert-butoxycarbonyle-4-iso-propyl-N⁵-benzyl-1,2,5-thiadiazolidine 1,2-dioxyde

Chemical Property of N²-tert-butoxycarbonyle-4-iso-propyl-N⁵-benzyl-1,2,5-thiadiazolidine 1,2-dioxyde

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N²-tert-butoxycarbonyle-4-iso-propyl-N⁵-benzyl-1,2,5-thiadiazolidine 1,2-dioxyde

There total 2 articles about N²-tert-butoxycarbonyle-4-iso-propyl-N⁵-benzyl-1,2,5-thiadiazolidine 1,2-dioxyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

N-tert-butyloxycarbonylsulfamoyl chloride (147000-89-3) + N-benzyl-N-(2-chloro-1-isopropylethyl)amine hydrochloride → N2-tert-butoxycarbonyle-4-iso-propyl-N5-benzyl-1,2,5-thiadiazolidine 1,2-dioxyde (263719-81-9)

Guidance literature:

With triethylamine; In dichloromethane; at 5 - 20 ℃; for 2h;

DOI:10.1016/S0040-4020(99)01025-X

Reference yield:

N-tert-butyloxycarbonylsulfamoyl chloride (147000-89-3) + benzyl-(1-chloromethyl-2-methyl-propyl)-amine → N2-tert-butoxycarbonyle-4-iso-propyl-N5-benzyl-1,2,5-thiadiazolidine 1,2-dioxyde (263719-81-9)

Guidance literature:

With triethylamine; In dichloromethane; at 0 ℃;

DOI:10.1080/15257770701544492

Reference yield: 96.0%

N2-tert-butoxycarbonyle-4-iso-propyl-N5-benzyl-1,2,5-thiadiazolidine 1,2-dioxyde (263719-81-9) → N5-benzyl-4-iso-propyl-1,2,5-thiadiazolidine 1,1-dioxyde (575455-32-2)

Guidance literature:

With iodine; for 0.166667h; under 20 Torr;

DOI:10.1002/jhet.5570410109

upstream raw materials:

N-tert-butyloxycarbonylsulfamoyl chloride

Downstream raw materials:

N⁵-benzyl-4-iso-propyl-1,2,5-thiadiazolidine 1,1-dioxyde