N-(2-azidoethyl)-N-methylaniline

Base Information

• Chemical Name: N-(2-azidoethyl)-N-methylaniline
• CAS No.: 1249429-26-2
• Molecular Formula: C₉H₁₂N₄
• Molecular Weight: 176.221
• Mol file: 1249429-26-2.mol

Synonyms:N-(2-azidoethyl)-N-methylaniline

Chemical Property of N-(2-azidoethyl)-N-methylaniline

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-(2-azidoethyl)-N-methylaniline

There total 5 articles about N-(2-azidoethyl)-N-methylaniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

2-(N-methyl-N-phenylamino)ethyl methanesulfonate → N-(2-azidoethyl)-N-methylaniline (1249429-26-2)

Guidance literature:

With sodium azide; In acetonitrile; at 80 ℃; for 5h;

DOI:10.1039/c3cc44798g

Reference yield: 34.0%

2-azido-O-methanesulphonyl-ethanol (75178-70-0) + N-methylaniline (100-61-8) → N-(2-azidoethyl)-N-methylaniline (1249429-26-2)

Guidance literature:

With potassium carbonate; potassium iodide; In acetonitrile; for 72h; Reflux;

DOI:10.1016/j.bmc.2015.06.044

Reference yield:

mesylate derivative (57590-62-2) → N-(2-azidoethyl)-N-methylaniline (1249429-26-2)

Guidance literature:

With sodium azide; In N,N-dimethyl-formamide; at 40 ℃;

DOI:10.1002/chem.201203427

upstream raw materials:

N-(2-hydroxyethyl)-N-methylaminobenzene

mesylate derivative

2-azido-O-methanesulphonyl-ethanol

N-methylaniline

Downstream raw materials:

C₃₁H₃₂N₉⁽¹⁺⁾*C₂F₃O₂^(1-)

C₄₁H₄₀N₉O₂⁽¹⁺⁾*C₂F₃O₂^(1-)

C₃₉H₄₁N₁₁O₇S*C₂HF₃O₂

(4-(((2-azidoethyl)methyl)amino)phenyl)bis(4-(dimethylamino)phenyl)methylium chloride