L-Alanine, N-2-propynyl-, methyl ester (9CI)

Base Information

Chemical Name:L-Alanine, N-2-propynyl-, methyl ester (9CI)
CAS No.:116366-79-1
Molecular Formula:C₇H₁₁NO₂
Molecular Weight:141.17
Hs Code.:
Mol file:116366-79-1.mol

Synonyms:L-Alanine,N-2-propynyl-, methyl ester (9CI); Methyl (S)-2-(propargylamino)propionate

Suppliers and Price of L-Alanine, N-2-propynyl-, methyl ester (9CI)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of L-Alanine, N-2-propynyl-, methyl ester (9CI)

Chemical Property:

PSA：38.33000
LogP:0.16160

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of L-Alanine, N-2-propynyl-, methyl ester (9CI)

There total 1 articles about L-Alanine, N-2-propynyl-, methyl ester (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 23.0%

: 2491-20-5
L-alanine methyl ester hydrochloride

: 106-96-7
propargyl bromide

: 116366-79-1
N-propargyl-L-alanine methyl ester

Guidance literature:: With potassium carbonate; In N,N-dimethyl-formamide; for 72h;
DOI:10.1016/S0040-4020(02)00129-1

Reference yield:

: 19078-72-9
bromo(phenyl)acetyl chloride

: 116366-79-1
N-propargyl-L-alanine methyl ester

: N-propargyl-N-[N-(p-methoxyphenyl)-(S)-phenylglycinyl]-(S)-alanine methyl ester

: N-propargyl-N-[N-(p-methoxyphenyl)-(R)-phenylglycinyl]-(S)-alanine methyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: triethylamine / dichloromethane / 3 h / 20 °C / Inert atmosphere

2: N-ethyl-N,N-diisopropylamine; tetra-(n-butyl)ammonium iodide / acetonitrile / 20 h / 20 °C / Inert atmosphere

With tetra-(n-butyl)ammonium iodide; triethylamine; N-ethyl-N,N-diisopropylamine; In dichloromethane; acetonitrile;
DOI:10.1002/ejoc.201301936