19078-72-9

Basic information

• Product Name: ALPHA-BROMOPHENYLACETYL CHLORIDE
• Synonyms: ALPHA-BROMOPHENYLACETYL CHLORIDE;2-bromo-2-phenylethanoyl chloride;Bromophenylacetic acid chloride;α-BroMophenylacetyl chloride
• CAS NO: 19078-72-9
• Molecular Formula: C₈H₆BrClO
• Molecular Weight: 233.49
• Mol File: 19078-72-9.mol
• Article Data: 35

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• BRN: 1943234
• CAS DataBase Reference: ALPHA-BROMOPHENYLACETYL CHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: ALPHA-BROMOPHENYLACETYL CHLORIDE(19078-72-9)
• EPA Substance Registry System: ALPHA-BROMOPHENYLACETYL CHLORIDE(19078-72-9)

Safety Data

• Hazard Codes: C
• Statements: 34
• Safety Statements: 26-36/37/39-45
• RIDADR: UN 3265 8 / PGII
• WGK Germany: 3
• Hazardous Substances Data: 19078-72-9(Hazardous Substances Data)

Upstream product

• 4870-65-9 2-bromophenylacetic acid 
• 103-80-0 phenylacetyl chloride 
• 2835-06-5 phenylglycin 
• 37859-24-8 2-(4-bromophenyl)acetyl chloride 
• 51009-27-9 [2-(3-Methoxy-phenyl)-ethyl]-phenyl-amine 
• 103-82-2 phenylacetic acid 
• 128-08-5 N-Bromosuccinimide 

Downstream Products

• 74004-88-9 2-bromo-2-phenylacetic acid benzyl ester 
• 41128-27-2 6β-((Ξ)-2-bromo-2-phenyl-acetylamino)-penicillanic acid 
• 18100-80-6 2,3,5-triphenyl-4-thiazolone 
• 59484-42-3 4-hydroxy-2,5-diphenyl-1,3-thiazole 
• 35132-16-2 tert-butyl α-bromo-α-phenylacetate 
• 104786-61-0 2-cyclohexylimino-3,4-dimethyl-6-phenyl-1,3,4-thiadiazan-5-one 
• 1440-73-9 (+/-)-α-Brom-phenylessigsaeure-<2,6-dimethyl-phenylester> 
• 102921-27-7 2-(5-oxo-2-(phenylmethylene)-2H-oxazol-4-yl)-5,5-dimethyl-4-thiazolidinecarboxylic acid 
• 263551-24-2 C₁₃H₁₀N₂O₂S 
• 57463-14-6 6-chloro-2-phenyl-4H-benzo[1,4]oxazin-3-one 
• 95616-56-1 C₂₆H₁₇N₃O₃S 
• 95647-47-5 C₂₂H₁₈N₂O₅S 
• 95616-55-0 C₂₂H₁₇N₃O₃S 

Relevant articles and documents

Systematic study on alkyl iodide initiators in living radical polymerization with organic catalysts

Several low-molar-mass alkyl iodides were studied as initiating dormant species in living radical polymerization with organic catalysts. Primary, secondary, and tertiary alkyl iodides with different stabilizing groups (ester, phenyl, and cyano groups) were systematically studied for the rational design of initiating alkyl iodides. The activation rate constants of these alkyl iodides were experimentally determined for quantitative comparison. These alkyl iodides were used in the polymerizations of methyl methacrylate and butyl acrylate to examine their initiation ability in these polymerizations. A telechelic polymer was prepared using an alkyl iodide with a functional group. Alkyl iodides with multi-initiating sites were also studied.

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Iron-Catalyzed Intramolecular C-H Amination of α-Azidyl Amides

Iron-catalyzed intramolecular C-H amination of aliphatic azides has recently emerged as a powerful tool for the preparation of nitrogen heterocycles. This paper reports that α-azidyl amides can be converted in high efficacy to imidazolinone compounds via intramolecular C(sp3)-H amination by the action of a simple catalytic system composed of FeCl2 and a β-diketiminate ligand. The reactions provide a simple and atom-economical approach toward polysubstituted imidazolinones.

Highly Enantioselective Hydrogenation of Amides via Dynamic Kinetic Resolution Under Low Pressure and Room Temperature

High-throughput screening and lab-scale optimization were combined to develop the catalytic system trans-RuCl2((S,S)-skewphos)((R,R)-dpen), 2-PrONa, and 2-PrOH. This system hydrogenates functionalized α-phenoxy and related amides at room temperature under 4 atm H2 pressure to give chiral alcohols with up to 99% yield and in greater than 99% enantiomeric excess via dynamic kinetic resolution.