(S)-2-benzyloxycarbonylaminopentanedioic acid 1-allyl ester 5-ethyl ester

Base Information

• Chemical Name: (S)-2-benzyloxycarbonylaminopentanedioic acid 1-allyl ester 5-ethyl ester
• CAS No.: 1245613-20-0
• Molecular Formula: C₁₈H₂₃NO₆
• Molecular Weight: 349.384
• Mol file: 1245613-20-0.mol

Synonyms:(S)-2-benzyloxycarbonylaminopentanedioic acid 1-allyl ester 5-ethyl ester

Chemical Property of (S)-2-benzyloxycarbonylaminopentanedioic acid 1-allyl ester 5-ethyl ester

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (S)-2-benzyloxycarbonylaminopentanedioic acid 1-allyl ester 5-ethyl ester

There total 1 articles about (S)-2-benzyloxycarbonylaminopentanedioic acid 1-allyl ester 5-ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

(S)-2-(benzyloxycarbonylamino)-5-ethoxy-5-oxopentanoic acid (35726-62-6,1029401-62-4) + allyl bromide (106-95-6) → (S)-2-benzyloxycarbonylaminopentanedioic acid 1-allyl ester 5-ethyl ester (1245613-20-0)

Guidance literature:

(S)-2-(benzyloxycarbonylamino)-5-ethoxy-5-oxopentanoic acid; With water; caesium carbonate; In N,N-dimethyl-formamide;

allyl bromide; In N,N-dimethyl-formamide; at 20 ℃;

DOI:10.1002/adsc.200900325

Reference yield: 73.0%

(S)-2-benzyloxycarbonylaminopentanedioic acid 1-allyl ester 5-ethyl ester (1245613-20-0) → (S)-2-(benzyloxycarbonylamino)-5-ethoxy-5-oxopentanoic acid (35726-62-6,1029401-62-4)

Guidance literature:

With methanol; recombinant Bacillus subtilis esterase double mutant E₁₈₈W/M₁₉₃C; In hexane; at 37 ℃; for 0.333333h; pH=7.4; regioselective reaction; aq. phosphate buffer; Enzymatic reaction;

DOI:10.1002/adsc.200900325

Reference yield:

(S)-2-benzyloxycarbonylaminopentanedioic acid 1-allyl ester 5-ethyl ester (1245613-20-0) → N-(benzyloxycarbonyl)glutamic acid α-allyl ester (1149729-33-8) + (S)-2-(benzyloxycarbonylamino)-5-ethoxy-5-oxopentanoic acid (35726-62-6,1029401-62-4)

Guidance literature:

With methanol; recombinant Bacillus subtilis esterase double mutant E₁₈₈W/M₁₉₃C; In hexane; at 37 ℃; for 0.75h; pH=7.4; regioselective reaction; aq. phosphate buffer; Enzymatic reaction;

DOI:10.1002/adsc.200900325

upstream raw materials:

(S)-2-(benzyloxycarbonylamino)-5-ethoxy-5-oxopentanoic acid

allyl bromide

Downstream raw materials:

N-(benzyloxycarbonyl)glutamic acid α-allyl ester

(S)-2-(benzyloxycarbonylamino)-5-ethoxy-5-oxopentanoic acid