6-chloronicotinic acid benzylamide

Base Information

• Chemical Name: 6-chloronicotinic acid benzylamide
• CAS No.: 224817-12-3
• Molecular Formula: C₁₃H₁₁ClN₂O
• Molecular Weight: 246.696

Synonyms:6-chloronicotinic acid benzylamide

Chemical Property of 6-chloronicotinic acid benzylamide

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

N-Benzyl-6-chloronicotinamide 95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 6-chloronicotinic acid benzylamide

There total 7 articles about 6-chloronicotinic acid benzylamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

6-chloro-3-pyridinecarboxylic acid ethyl ester (49608-01-7) + benzylamine (100-46-9) → 6-chloronicotinic acid benzylamide (224817-12-3)

Guidance literature:

With lanthanum(lll) triflate; at 50 ℃; for 24h; chemoselective reaction; Inert atmosphere;

DOI:10.1021/ol500593v

Reference yield: 89.0%

6-Chloronicotinoyl chloride (58757-38-3) + benzylamine (100-46-9) → 6-chloronicotinic acid benzylamide (224817-12-3)

Guidance literature:

With triethylamine; In dichloromethane; at 20 ℃; for 3h; Cooling with ice;

Reference yield: 64.0%

6-Chloro-3-pyridinecarboxylic acid (5326-23-8) + benzylamine (100-46-9) → 6-chloronicotinic acid benzylamide (224817-12-3)

Guidance literature:

With triethylamine; HATU; at 20 ℃;

upstream raw materials:

6-Chloronicotinoyl chloride

benzylamine

6-Chloro-3-pyridinecarboxylic acid

6-chloro-3-pyridinecarboxylic acid ethyl ester

Downstream raw materials:

N-benzyl-6-chloro-4-(o-tolyl)nicotinamide

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 224817-12-3 6-chloronicotinic acid benzylamide

Send

Send

Metric Ton KG G Pound L ML

Send

Send