3-(4-Chlorophenyl)-2-fluoro-3-oxopropanenitrile

Base Information

• Chemical Name: 3-(4-Chlorophenyl)-2-fluoro-3-oxopropanenitrile
• CAS No.: 1263063-13-3
• Molecular Formula: C₉H₅ClFNO
• Molecular Weight: 197.596
• Hs Code.: 2926907090
• Mol file: 1263063-13-3.mol

Synonyms:C₉H₅ClFNO

Chemical Property of 3-(4-Chlorophenyl)-2-fluoro-3-oxopropanenitrile

Chemical Property:

Purity/Quality:

98%min ^*data from raw suppliers

3-(4-Chlorophenyl)-2-fluoro-3-oxopropanenitrile >95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-(4-Chlorophenyl)-2-fluoro-3-oxopropanenitrile

There total 1 articles about 3-(4-Chlorophenyl)-2-fluoro-3-oxopropanenitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

fluoroacetonitrile (503-20-8) + 4-chloro-benzoyl chloride (122-01-0) → C9H5ClFNO (1263063-13-3)

Guidance literature:

fluoroacetonitrile; 4-chloro-benzoyl chloride; With lithium hexamethyldisilazane; In tetrahydrofuran; at -78 - 20 ℃; Inert atmosphere;

With hydrogenchloride; In tetrahydrofuran; water; at 20 ℃; pH=2;

DOI:10.1080/00397910903277912

Reference yield:

C9H5ClFNO (1263063-13-3) → 5-(4-chloro-phenyl)-4-fluoro-2H-pyrazol-3-ylamine (1246384-94-0)

Guidance literature:

With hydrazine hydrate; In ethanol; for 18h; Reflux;

DOI:10.1080/00397910903277912

upstream raw materials:

fluoroacetonitrile

4-chloro-benzoyl chloride

Downstream raw materials:

5-(4-chloro-phenyl)-4-fluoro-2H-pyrazol-3-ylamine

Refernces