(5R,4S,2S)-4-acetoxy-5-((phenylmethoxy)methyl)-1,2-pyrrolidinedicarboxylic acid 2-methyl 1-(phenylmethyl) diester

Base Information

Chemical Name:(5R,4S,2S)-4-acetoxy-5-((phenylmethoxy)methyl)-1,2-pyrrolidinedicarboxylic acid 2-methyl 1-(phenylmethyl) diester
CAS No.:128359-94-4
Molecular Formula:C₂₄H₂₇NO₇
Molecular Weight:441.481
Hs Code.:

Synonyms:(5R,4S,2S)-4-acetoxy-5-((phenylmethoxy)methyl)-1,2-pyrrolidinedicarboxylic acid 2-methyl 1-(phenylmethyl) diester

Suppliers and Price of (5R,4S,2S)-4-acetoxy-5-((phenylmethoxy)methyl)-1,2-pyrrolidinedicarboxylic acid 2-methyl 1-(phenylmethyl) diester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (5R,4S,2S)-4-acetoxy-5-((phenylmethoxy)methyl)-1,2-pyrrolidinedicarboxylic acid 2-methyl 1-(phenylmethyl) diester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (5R,4S,2S)-4-acetoxy-5-((phenylmethoxy)methyl)-1,2-pyrrolidinedicarboxylic acid 2-methyl 1-(phenylmethyl) diester

There total 16 articles about (5R,4S,2S)-4-acetoxy-5-((phenylmethoxy)methyl)-1,2-pyrrolidinedicarboxylic acid 2-methyl 1-(phenylmethyl) diester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 100-39-0
benzyl bromide

: 132592-31-5
(5R,4S,2S)-4-acetoxy-5-(hydroxymethyl)-1,2-pyrrolidinedicarboxylic acid 2-methyl 1-(phenylmethyl) diester

: 128359-94-4
(5R,4S,2S)-4-acetoxy-5-((phenylmethoxy)methyl)-1,2-pyrrolidinedicarboxylic acid 2-methyl 1-(phenylmethyl) diester

Guidance literature:: With silver(l) oxide; In dichloromethane; Heating;
DOI:10.1021/jo00305a007

Reference yield: 90.0%

: 81927-55-1
O-benzyl 2,2,2-trichloroacetimidate

: 132592-31-5
(5R,4S,2S)-4-acetoxy-5-(hydroxymethyl)-1,2-pyrrolidinedicarboxylic acid 2-methyl 1-(phenylmethyl) diester

: 128359-94-4
(5R,4S,2S)-4-acetoxy-5-((phenylmethoxy)methyl)-1,2-pyrrolidinedicarboxylic acid 2-methyl 1-(phenylmethyl) diester

Guidance literature:: With trifluorormethanesulfonic acid; In dichloromethane;
DOI:10.1021/acsinfecdis.8b00105

Reference yield: 48.0%

: 81927-55-1
O-benzyl 2,2,2-trichloroacetimidate

: 128388-09-0
(5R,4S,2S)-4-acetoxy-5-hydroxymethyl-1,2-pyrrolidinedicarboxylic acid 2-methyl 1-(2-(trimethylsilyl)ethyl) diester

: 128359-94-4
(5R,4S,2S)-4-acetoxy-5-((phenylmethoxy)methyl)-1,2-pyrrolidinedicarboxylic acid 2-methyl 1-(phenylmethyl) diester

Guidance literature:: With trifluorormethanesulfonic acid; In cyclohexane; for 1h; Mechanism; other O-2-(trimethylsilyl)ethyl- or O-tert-butyl carbamates;
DOI:10.1021/jo00304a035