non-8-ene-2,5-diol

Base Information

• Chemical Name: non-8-ene-2,5-diol
• CAS No.: 132381-58-9
• Molecular Formula: C₉H₁₈O₂
• Molecular Weight: 158.241
• Mol file: 132381-58-9.mol

Synonyms:non-8-ene-2,5-diol

Chemical Property of non-8-ene-2,5-diol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of non-8-ene-2,5-diol

There total 1 articles about non-8-ene-2,5-diol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

5-methyl-tetrahydro-furan-2-ol (18545-25-0) + 1-bromo-4-butene (5162-44-7) → non-8-ene-2,5-diol (132381-58-9)

Guidance literature:

With magnesium; Yield given. Multistep reaction; 1) Et₂O; 2) Et₂O;

DOI:10.1246/bcsj.63.3560

Reference yield:

non-8-ene-2,5-diol (132381-58-9) → 5-((5,8-bis((tert-butyldimethylsilyl)oxy)nonyl)sulfonyl)-1-phenyl-1H-tetrazole

Guidance literature:

Multi-step reaction with 4 steps

1.1: 1H-imidazole / N,N-dimethyl-formamide / Inert atmosphere

2.1: borane-THF / tetrahydrofuran / 3 h / 20 °C / Inert atmosphere

2.2: 3 h / Inert atmosphere

3.1: triphenylphosphine; diethylazodicarboxylate / tetrahydrofuran; toluene / 0.33 h / Inert atmosphere

4.1: dihydrogen peroxide; ammonium molybdate tetrahydrate / water; ethanol / 3 h / 0 - 20 °C / Inert atmosphere

With 1H-imidazole; borane-THF; ammonium molybdate tetrahydrate; dihydrogen peroxide; triphenylphosphine; diethylazodicarboxylate; In tetrahydrofuran; ethanol; water; N,N-dimethyl-formamide; toluene; 3.1: |Mitsunobu Displacement;

DOI:10.1016/j.tet.2016.03.041

Reference yield:

non-8-ene-2,5-diol (132381-58-9) → C28H52N4O2SSi2

Guidance literature:

Multi-step reaction with 3 steps

1.1: 1H-imidazole / N,N-dimethyl-formamide / Inert atmosphere

2.1: borane-THF / tetrahydrofuran / 3 h / 20 °C / Inert atmosphere

2.2: 3 h / Inert atmosphere

3.1: triphenylphosphine; diethylazodicarboxylate / tetrahydrofuran; toluene / 0.33 h / Inert atmosphere

With 1H-imidazole; borane-THF; triphenylphosphine; diethylazodicarboxylate; In tetrahydrofuran; N,N-dimethyl-formamide; toluene; 3.1: |Mitsunobu Displacement;

DOI:10.1016/j.tet.2016.03.041

upstream raw materials:

5-methyl-tetrahydro-furan-2-ol

1-bromo-4-butene

Refernces