Technology Process of 3β-chloroacetoxy-3α-methyl-4α-(p-nitrobenzoyloxymethyl)-7β-phenoxyacetamidocepham
There total 7 articles about 3β-chloroacetoxy-3α-methyl-4α-(p-nitrobenzoyloxymethyl)-7β-phenoxyacetamidocepham which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 62 percent / pyridine / tetrahydrofuran; benzene / 15 h / 0 deg C -> room temnperature
2: 54 percent / 90percent m-chloroperbenzoic acis / CH2Cl2 / 1 h / 0 °C
3: 83 percent / toluene / 2 h / Heating
4: 0.055 g / AgOAc / CH2Cl2 / 4 h / Ambient temperature; cyclisation reaction with Br2; cyclisation reaction of azetidinone disulphides with Br2 in CH2Cl2 and CHCH2CO2H-AgOAC in CH2Cl2; interconversion reactions of penam and cepham derivatives obtained, effect of subtituents nature
With
pyridine; silver(I) acetate; 3-chloro-benzenecarboperoxoic acid;
In
tetrahydrofuran; dichloromethane; toluene; benzene;
DOI:10.1039/P19840000413
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 62 percent / pyridine / tetrahydrofuran; benzene / 15 h / 0 deg C -> room temnperature
2: 54 percent / 90percent m-chloroperbenzoic acis / CH2Cl2 / 1 h / 0 °C
3: 83 percent / toluene / 2 h / Heating
4: 0.055 g / AgOAc / CH2Cl2 / 4 h / Ambient temperature; cyclisation reaction with Br2; cyclisation reaction of azetidinone disulphides with Br2 in CH2Cl2 and CHCH2CO2H-AgOAC in CH2Cl2; interconversion reactions of penam and cepham derivatives obtained, effect of subtituents nature
With
pyridine; silver(I) acetate; 3-chloro-benzenecarboperoxoic acid;
In
tetrahydrofuran; dichloromethane; toluene; benzene;
DOI:10.1039/P19840000413
- Guidance literature:
-
Multi-step reaction with 5 steps
1: NaBH4 / tetrahydrofuran / 0.5 h / Ambient temperature
2: 62 percent / pyridine / tetrahydrofuran; benzene / 15 h / 0 deg C -> room temnperature
3: 54 percent / 90percent m-chloroperbenzoic acis / CH2Cl2 / 1 h / 0 °C
4: 83 percent / toluene / 2 h / Heating
5: 0.055 g / AgOAc / CH2Cl2 / 4 h / Ambient temperature; cyclisation reaction with Br2; cyclisation reaction of azetidinone disulphides with Br2 in CH2Cl2 and CHCH2CO2H-AgOAC in CH2Cl2; interconversion reactions of penam and cepham derivatives obtained, effect of subtituents nature
With
pyridine; sodium tetrahydroborate; silver(I) acetate; 3-chloro-benzenecarboperoxoic acid;
In
tetrahydrofuran; dichloromethane; toluene; benzene;
DOI:10.1039/P19840000413
