Technology Process of trans-(Pd(C6H4(C(O)Me)-2)Br(PPh3)2)
There total 1 articles about trans-(Pd(C6H4(C(O)Me)-2)Br(PPh3)2) which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
In
toluene;
Pd(dba)2, PPh3 and org. compd. mixed under N2 in toluene, refluxed for 10 min, residue extd. with CH2Cl2, filtered over anhyd. MgSO4; evapd., Et2O added, filtered, washed with Et2O, dried, elem. anal.;
DOI:10.1021/om9905963
- Guidance literature:
-
With
(PdCl2(NCPh)2); NaBr;
In
dichloromethane;
Cl complex added to soln. of Pd complex in CH2Cl2, stirred for 30 min, added excess of NaBr , stirred for 10 min, filtered, washed with CH2Cl2; combined mother liquors concd. nearly to dryness, added Et2O, filtered, washed with Et2O, dried in air, chromy. (preparative TLC, hexane/CH2Cl2-1:3), elem. anal.;
DOI:10.1021/om9905963
- Guidance literature:
-
In
dichloromethane;
byproducts: PPh3; mixing of Me2C6H3NC (3 equiv.) and (Pd(2-acetylphenyl)Br(PPh3)2) (1 equiv.) in CH2Cl2 under N2; immediately evapn., addn. of Et2O, partially evapn., cooling, pptn., filtration in air, washing with cold Et2O;
DOI:10.1021/om020380s
