p-methylphenyl 2,3-di-O-benzyl-4,6-O-p-chlorobenzylidene-thio-α-D-mannopyranoside

Base Information

• Chemical Name: p-methylphenyl 2,3-di-O-benzyl-4,6-O-p-chlorobenzylidene-thio-α-D-mannopyranoside
• CAS No.: 952051-06-8
• Molecular Formula: C₃₄H₃₃ClO₅S
• Molecular Weight: 589.152
• Mol file: 952051-06-8.mol

Synonyms:p-methylphenyl 2,3-di-O-benzyl-4,6-O-p-chlorobenzylidene-thio-α-D-mannopyranoside

Chemical Property of p-methylphenyl 2,3-di-O-benzyl-4,6-O-p-chlorobenzylidene-thio-α-D-mannopyranoside

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of p-methylphenyl 2,3-di-O-benzyl-4,6-O-p-chlorobenzylidene-thio-α-D-mannopyranoside

There total 1 articles about p-methylphenyl 2,3-di-O-benzyl-4,6-O-p-chlorobenzylidene-thio-α-D-mannopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

p-methylphenyl 4,6-O-p-chlorobenzylidene-thio-α-D-mannopyranoside + benzyl bromide (100-39-0) → p-methylphenyl 2,3-di-O-benzyl-4,6-O-p-chlorobenzylidene-thio-α-D-mannopyranoside (952051-06-8)

Guidance literature:

p-methylphenyl 4,6-O-p-chlorobenzylidene-thio-α-D-mannopyranoside; With sodium hydride; In N,N-dimethyl-formamide; at 0 ℃; for 1h;

benzyl bromide; In N,N-dimethyl-formamide; at 0 - 20 ℃; Further stages.;

DOI:10.1021/ja072440x

Reference yield: 68.0%

p-methylphenyl 2,3-di-O-benzyl-4,6-O-p-chlorobenzylidene-thio-α-D-mannopyranoside (952051-06-8) + methyl 2,3-O-isopropylidene-α-L-rhamnoside (14133-63-2) → methyl 2,3-di-O-benzyl-4,6-O-p-chlorobenzylidene-β-D-mannopyranosyl-(1-4)-2,3-O-isopropylidene-α-L-rhamnopyranoside

Guidance literature:

p-methylphenyl 2,3-di-O-benzyl-4,6-O-p-chlorobenzylidene-thio-α-D-mannopyranoside; With trifluorormethanesulfonic acid; tetrabutylammonium trifluoromethylsulfonate; In dichloromethane; at -78 ℃; Electrochemical reaction;

methyl 2,3-O-isopropylidene-α-L-rhamnoside; In dichloromethane; at -78 ℃; for 1h; Further stages.;

DOI:10.1021/ja072440x

Reference yield:

p-methylphenyl 2,3-di-O-benzyl-4,6-O-p-chlorobenzylidene-thio-α-D-mannopyranoside (952051-06-8) + tetrabutylammonium trifluoromethylsulfonate (35895-70-6) → triflyl 2,3-di-O-benzyl-4,6-O-p-chlorobenzylidene-α-D-mannopyranoside

Guidance literature:

With trifluorormethanesulfonic acid; tetrabutylammonium trifluoromethylsulfonate; In dichloromethane-d2; at -78 ℃; Electrochemical reaction;

DOI:10.1021/ja072440x

upstream raw materials:

benzyl bromide