(S)-Dimethylthiocarbamoylsulfanyl-phenyl-acetic acid ethyl ester

Base Information

• Chemical Name: (S)-Dimethylthiocarbamoylsulfanyl-phenyl-acetic acid ethyl ester
• CAS No.: 190583-69-8
• Molecular Formula: C₁₃H₁₇NO₂S₂
• Molecular Weight: 283.415
• Mol file: 190583-69-8.mol

Synonyms:(S)-Dimethylthiocarbamoylsulfanyl-phenyl-acetic acid ethyl ester

Chemical Property of (S)-Dimethylthiocarbamoylsulfanyl-phenyl-acetic acid ethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (S)-Dimethylthiocarbamoylsulfanyl-phenyl-acetic acid ethyl ester

There total 1 articles about (S)-Dimethylthiocarbamoylsulfanyl-phenyl-acetic acid ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

(R)-mandelic acid ethyl ester (10606-72-1) + Ziram → (S)-Dimethylthiocarbamoylsulfanyl-phenyl-acetic acid ethyl ester (190583-69-8)

Guidance literature:

With triphenylphosphine; diethylazodicarboxylate; In toluene; for 24h; Ambient temperature;

DOI:10.1021/jo962286p

Reference yield: 86.0%

(S)-Dimethylthiocarbamoylsulfanyl-phenyl-acetic acid ethyl ester (190583-69-8) → (S)-2-mercapto-2-phenylethanol (131981-97-0)

Guidance literature:

With lithium aluminium tetrahydride; In diethyl ether; for 4h; Heating;

DOI:10.1021/jo962286p

Reference yield:

(S)-Dimethylthiocarbamoylsulfanyl-phenyl-acetic acid ethyl ester (190583-69-8) → (S)-2-((S)-(Z)-4-Methoxy-buta-1,3-diene-2-sulfinyl)-2-phenyl-ethanol

Guidance literature:

Multi-step reaction with 4 steps

1: 86 percent / LiAlH₄ / diethyl ether / 4 h / Heating

2: 84 percent / benzyltrimethylammonium hydroxide / tetrahydrofuran; methanol / -78 - 20 °C

3: 89 percent / m-chloroperoxybenzoic acid / CH₂Cl₂ / -15 - 20 °C

4: 30 percent / toluene / 0.75 h / Heating

With lithium aluminium tetrahydride; N-benzyl-trimethylammonium hydroxide; 3-chloro-benzenecarboperoxoic acid; In tetrahydrofuran; methanol; diethyl ether; dichloromethane; toluene;

DOI:10.1021/jo962286p

upstream raw materials:

(R)-mandelic acid ethyl ester

Downstream raw materials:

(S)-2-mercapto-2-phenylethanol

3-((S)-2-Hydroxy-1-phenyl-ethylsulfanyl)-propionitrile

(S)-2-((S)-(E)-4-Methoxy-buta-1,3-diene-2-sulfinyl)-2-phenyl-ethanol

3-((R)-(S)-2-Hydroxy-1-phenyl-ethanesulfinyl)-propionitrile