4,4,5,5-tetramethyl-2-(4-phenyl-1-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)propan-2-yl)-1,3,2-dioxaborolane

Base Information

• Chemical Name: 4,4,5,5-tetramethyl-2-(4-phenyl-1-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)propan-2-yl)-1,3,2-dioxaborolane
• CAS No.: 1172611-59-4
• Molecular Formula: C₂₁H₃₄B₂O₄
• Molecular Weight: 372.121
• Mol file: 1172611-59-4.mol

Synonyms:4,4,5,5-tetramethyl-2-(4-phenyl-1-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)propan-2-yl)-1,3,2-dioxaborolane

Chemical Property of 4,4,5,5-tetramethyl-2-(4-phenyl-1-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)propan-2-yl)-1,3,2-dioxaborolane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4,4,5,5-tetramethyl-2-(4-phenyl-1-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)propan-2-yl)-1,3,2-dioxaborolane

There total 11 articles about 4,4,5,5-tetramethyl-2-(4-phenyl-1-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)propan-2-yl)-1,3,2-dioxaborolane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

allylbenzene (300-57-2,57807-91-7) + bis(pinacol)diborane (73183-34-3) → 4,4,5,5-tetramethyl-2-(4-phenyl-1-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)propan-2-yl)-1,3,2-dioxaborolane (1172611-59-4)

Guidance literature:

With C₃₇H₆₀N₂OPtSi₂; In n-heptane; at 20 ℃; for 20h; Schlenk technique; Inert atmosphere;

DOI:10.1016/j.jorganchem.2020.121140

Reference yield: 82.0%

propargyl benzene (10147-11-2) + bis(pinacol)diborane (73183-34-3) → 4,4,5,5-tetramethyl-2-(4-phenyl-1-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)propan-2-yl)-1,3,2-dioxaborolane (1172611-59-4)

Guidance literature:

With caesium carbonate; In methanol; acetonitrile; at 80 ℃; for 12h; Reagent/catalyst; regioselective reaction; Inert atmosphere;

DOI:10.1039/c7gc01161j

Reference yield: 68.0%

benzyl chloride (100-44-7) + pinacol vinylboronate (75927-49-0) + bis(pinacol)diborane (73183-34-3) → 4,4,5,5-tetramethyl-2-(4-phenyl-1-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)propan-2-yl)-1,3,2-dioxaborolane (1172611-59-4)

Guidance literature:

With (1,3-dimesitylimidazolidin-2-yl)copper(I) chloride; potassium tert-butylate; In tetrahydrofuran; N,N-dimethyl-formamide; at 20 ℃; for 7h; Inert atmosphere; Schlenk technique;

DOI:10.1055/s-0033-1341267

upstream raw materials:

2,2'‐(2‐phenylethane‐1,1‐diyl)bis(4,4,5,5‐tetramethyl‐1,3,2‐dioxaborolane)

(chloromethyl)lithium

benzyl chloride

allylbenzene

Downstream raw materials:

(S)-(-)-3-phenyl-1,2-propanediol

(R)-3-phenylpropane-1,2-diol