10-{2-[(2s)-1-Methylpiperidin-2-Yl]ethyl}-2-(Methylsulfanyl)-10h-Phenothiazine

Base Information Edit

Chemical Name:10-{2-[(2s)-1-Methylpiperidin-2-Yl]ethyl}-2-(Methylsulfanyl)-10h-Phenothiazine
CAS No.:114488-10-7
Molecular Formula:C₂₁H₂₆N₂S₂
Molecular Weight:370.583
Hs Code.:
ChEMBL ID:CHEMBL3133835
DSSTox Substance ID:DTXSID301015457
Nikkaji Number:J1.241.418H
Wikidata:Q27462825
Mol file:114488-10-7.mol

Synonyms:10-{2-[(2s)-1-Methylpiperidin-2-Yl]ethyl}-2-(Methylsulfanyl)-10h-Phenothiazine;114488-10-7;10-[2-[(2S)-1-methylpiperidin-2-yl]ethyl]-2-methylsulfanylphenothiazine;(-)-Thioridazine;LZU;SCHEMBL2577719;CHEMBL3133835;DTXSID301015457;PD070250;EN300-37099885;Q27462825

Suppliers and Price of 10-{2-[(2s)-1-Methylpiperidin-2-Yl]ethyl}-2-(Methylsulfanyl)-10h-Phenothiazine

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 10-{2-[(2s)-1-Methylpiperidin-2-Yl]ethyl}-2-(Methylsulfanyl)-10h-Phenothiazine Edit

Chemical Property:

Vapor Pressure:9.65E-11mmHg at 25°C
Refractive Index:1.676
Boiling Point:515.7°C at 760 mmHg
Flash Point:265.7°C
PSA：57.08000
Density:1.23g/cm³
LogP:5.88850
XLogP3:5.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:370.15374118
Heavy Atom Count:25
Complexity:432

Purity/Quality:: 99%min ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CN1CCCCC1CCN2C3=CC=CC=C3SC4=C2C=C(C=C4)SC
Isomeric SMILES:CN1CCCC[C@H]1CCN2C3=CC=CC=C3SC4=C2C=C(C=C4)SC

Technology Process of 10-{2-[(2s)-1-Methylpiperidin-2-Yl]ethyl}-2-(Methylsulfanyl)-10h-Phenothiazine

There total 25 articles about 10-{2-[(2s)-1-Methylpiperidin-2-Yl]ethyl}-2-(Methylsulfanyl)-10h-Phenothiazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 26.0%

: (1R,2S,5R)-2-isopropyl-5-methylcyclohexyl 2-{2-[2-(methylthio)-10H-phenothiazin-10-yl]ethyl}piperidine-1-carboxylate

: 50-52-2,52496-67-0,57129-06-3,114488-10-7
thioridazine

Guidance literature:: With lithium aluminium tetrahydride; In tetrahydrofuran; at 0 - 50 ℃; for 18h; Inert atmosphere;

Reference yield:

: 129846-85-1
N-(2-(1-methyl-2-piperidynyl)ethyl)-2-(2-fluorophenylthio)-5-(methylthio)aniline

: 50-52-2,52496-67-0,57129-06-3,114488-10-7
thioridazine

Guidance literature:: With sodium hydride; In dimethyl sulfoxide; for 6.5h; Heating;

Reference yield:

: 1199-36-6
1-chloro-4-(methylthio)-2-nitrobenzene

: 50-52-2,52496-67-0,57129-06-3,114488-10-7
thioridazine

Guidance literature:: Multi-step reaction with 4 steps

1: 89 percent / K₂CO₃ / dimethylformamide / 3.5 h / 60 °C

2: 99 percent / active carbon, N₂H₄, FeCl₃*6H₂O / ethanol / 10 h / Heating

3: 23 percent / 80percent NaH / xylene / 3 h / Heating

4: 80percent NaH / dimethylsulfoxide / 6.5 h / Heating

With iron(III) chloride; sodium hydride; potassium carbonate; pyrographite; hydrazine hydrate; In ethanol; dimethyl sulfoxide; N,N-dimethyl-formamide; xylene;