(RS)-N¹-<11-<alanyl>amino>undecanoyl>-N⁴,N⁸-bis(toluol-4-sulfonyl)spermidin

Base Information

• Chemical Name: (RS)-N¹-<11-<alanyl>amino>undecanoyl>-N⁴,N⁸-bis(toluol-4-sulfonyl)spermidin
• CAS No.: 150672-05-2
• Molecular Formula: C₄₆H₆₉N₅O₁₀S₂
• Molecular Weight: 916.213
• Mol file: 150672-05-2.mol

Synonyms:(RS)-N¹-<11-<alanyl>amino>undecanoyl>-N⁴,N⁸-bis(toluol-4-sulfonyl)spermidin

Chemical Property of (RS)-N¹-<11-<alanyl>amino>undecanoyl>-N⁴,N⁸-bis(toluol-4-sulfonyl)spermidin

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (RS)-N¹-<11-<alanyl>amino>undecanoyl>-N⁴,N⁸-bis(toluol-4-sulfonyl)spermidin

There total 5 articles about (RS)-N¹-<11-<alanyl>amino>undecanoyl>-N⁴,N⁸-bis(toluol-4-sulfonyl)spermidin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

11-aminoundecanoic acid (2432-99-7,25587-80-8,84029-94-7) → (RS)-N1-<11-<alanyl>amino>undecanoyl>-N4,N8-bis(toluol-4-sulfonyl)spermidin (150672-05-2)

Guidance literature:

Multi-step reaction with 4 steps

1: 78 percent / NaOH / H₂O / 0 °C

2: 1) 1,1'-carbonyldiimidazole / 1) THF, r.t., 2 h, 2) THF, r.t., 1 h

3: H₂ / 10percent Pd/C / methanol / 24 h / 760 Torr

4: 1) 1,1'-carbonyldiimidazole / 1) THF, r.t, 2 h, 2) THF, r.t., 1 h

With sodium hydroxide; hydrogen; 1,1'-carbonyldiimidazole; palladium on activated charcoal; In methanol; water;

DOI:10.1002/hlca.19930760304

Reference yield:

11-<(Benzyloxycarbonyl)amino>undecansaeure (3422-91-1) → (RS)-N1-<11-<alanyl>amino>undecanoyl>-N4,N8-bis(toluol-4-sulfonyl)spermidin (150672-05-2)

Guidance literature:

Multi-step reaction with 3 steps

1: 1) 1,1'-carbonyldiimidazole / 1) THF, r.t., 2 h, 2) THF, r.t., 1 h

2: H₂ / 10percent Pd/C / methanol / 24 h / 760 Torr

3: 1) 1,1'-carbonyldiimidazole / 1) THF, r.t, 2 h, 2) THF, r.t., 1 h

With hydrogen; 1,1'-carbonyldiimidazole; palladium on activated charcoal; In methanol;

DOI:10.1002/hlca.19930760304

Reference yield:

N1-<11-<(Benzyloxycarbonyl)amino>undecanoyl>-N4,N8-bis(toluol-4-sulfonyl)spermidin (150671-88-8) → (RS)-N1-<11-<alanyl>amino>undecanoyl>-N4,N8-bis(toluol-4-sulfonyl)spermidin (150672-05-2)

Guidance literature:

Multi-step reaction with 2 steps

1: H₂ / 10percent Pd/C / methanol / 24 h / 760 Torr

2: 1) 1,1'-carbonyldiimidazole / 1) THF, r.t, 2 h, 2) THF, r.t., 1 h

With hydrogen; 1,1'-carbonyldiimidazole; palladium on activated charcoal; In methanol;

DOI:10.1002/hlca.19930760304

upstream raw materials:

N-<(3,4,5-Trimethoxyphenyl)acetyl>-DL-alanin

N¹-(11-Aminoundecanoyl)-N⁴,N⁸-bis(toluol-4-sulfonyl)spermidin

11-aminoundecanoic acid

11-<(Benzyloxycarbonyl)amino>undecansaeure