Technology Process of 1-benzyloxy-2,5-di-(tert-butyl)-3-ethoxycarbonyl-4-hydroxypyrrole
There total 4 articles about 1-benzyloxy-2,5-di-(tert-butyl)-3-ethoxycarbonyl-4-hydroxypyrrole which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: potassium carbonate / dimethyl sulfoxide / 3 h / 20 °C
2.1: trichlorophosphate / neat (no solvent) / 0.25 h / Cooling with ice
2.2: 255 / 3 h / 20 - 50 °C
2.3: 50 °C
3.1: Oxone / N,N-dimethyl-formamide / 16 h / 20 °C
4.1: potassium hydrogensulfate; sodium dithionite / ethanol / 40 h / 20 °C
With
Oxone; potassium hydrogensulfate; sodium dithionite; potassium carbonate; trichlorophosphate;
In
ethanol; dimethyl sulfoxide; N,N-dimethyl-formamide;
3.1: |Baeyer-Villiger Ketone Oxidation;
DOI:10.1016/j.tetlet.2014.04.004
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: trichlorophosphate / neat (no solvent) / 0.25 h / Cooling with ice
1.2: 255 / 3 h / 20 - 50 °C
1.3: 50 °C
2.1: Oxone / N,N-dimethyl-formamide / 16 h / 20 °C
3.1: potassium hydrogensulfate; sodium dithionite / ethanol / 40 h / 20 °C
With
Oxone; potassium hydrogensulfate; sodium dithionite; trichlorophosphate;
In
ethanol; N,N-dimethyl-formamide;
2.1: |Baeyer-Villiger Ketone Oxidation;
DOI:10.1016/j.tetlet.2014.04.004
