1,2-bis-(5-[4-(2-{2-[2-(2-{2-hydrazidocarbomethoxy}ethoxy)-ethoxy]-ethoxy}-ethoxy)-phenyl]-2-methyl-thiophene-3-yl)-perfluorocyclopentene

Base Information

• Chemical Name: 1,2-bis-(5-[4-(2-{2-[2-(2-{2-hydrazidocarbomethoxy}ethoxy)-ethoxy]-ethoxy}-ethoxy)-phenyl]-2-methyl-thiophene-3-yl)-perfluorocyclopentene
• CAS No.: 1340599-93-0
• Molecular Formula: C₄₇H₅₈F₆N₄O₁₂S₂
• Molecular Weight: 1049.12
• Mol file: 1340599-93-0.mol

Synonyms:1,2-bis-(5-[4-(2-{2-[2-(2-{2-hydrazidocarbomethoxy}ethoxy)-ethoxy]-ethoxy}-ethoxy)-phenyl]-2-methyl-thiophene-3-yl)-perfluorocyclopentene

Chemical Property of 1,2-bis-(5-[4-(2-{2-[2-(2-{2-hydrazidocarbomethoxy}ethoxy)-ethoxy]-ethoxy}-ethoxy)-phenyl]-2-methyl-thiophene-3-yl)-perfluorocyclopentene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1,2-bis-(5-[4-(2-{2-[2-(2-{2-hydrazidocarbomethoxy}ethoxy)-ethoxy]-ethoxy}-ethoxy)-phenyl]-2-methyl-thiophene-3-yl)-perfluorocyclopentene

There total 6 articles about 1,2-bis-(5-[4-(2-{2-[2-(2-{2-hydrazidocarbomethoxy}ethoxy)-ethoxy]-ethoxy}-ethoxy)-phenyl]-2-methyl-thiophene-3-yl)-perfluorocyclopentene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 42.0%

1,2-bis-(5-[4-(2-{2-[2-(2-{2-methoxycarbomethoxy}-ethoxy)-ethoxy]-ethoxy}-ethoxy)-phenyl]-2-methyl-thiophene-3-yl)-perfluorocyclopentene (1147082-58-3) → 1,2-bis-(5-[4-(2-{2-[2-(2-{2-hydrazidocarbomethoxy}ethoxy)-ethoxy]-ethoxy}-ethoxy)-phenyl]-2-methyl-thiophene-3-yl)-perfluorocyclopentene (1340599-93-0)

Guidance literature:

With hydrazine hydrate; In methanol; at 70 ℃; for 14h;

DOI:10.1039/c1cc14041h

Reference yield:

3-bromo-5-(4-methoxyphenyl)-2-methylthiophene (156686-75-8) → 1,2-bis-(5-[4-(2-{2-[2-(2-{2-hydrazidocarbomethoxy}ethoxy)-ethoxy]-ethoxy}-ethoxy)-phenyl]-2-methyl-thiophene-3-yl)-perfluorocyclopentene (1340599-93-0)

Guidance literature:

Multi-step reaction with 4 steps

1: n-butyllithium / tetrahydrofuran / 6 h

2: boron tribromide

3: potassium carbonate / acetonitrile / 16 h / Inert atmosphere; Reflux

4: hydrazine hydrate / methanol / 14 h / 70 °C

With n-butyllithium; boron tribromide; potassium carbonate; hydrazine hydrate; In tetrahydrofuran; methanol; acetonitrile;

DOI:10.1039/c1cc14041h

Reference yield:

1,2-Bis-<5'-(4''-hydroxyphenyl)-2'-methylthien-3'-yl>perfluorocyclopentene (156686-73-6) → 1,2-bis-(5-[4-(2-{2-[2-(2-{2-hydrazidocarbomethoxy}ethoxy)-ethoxy]-ethoxy}-ethoxy)-phenyl]-2-methyl-thiophene-3-yl)-perfluorocyclopentene (1340599-93-0)

Guidance literature:

Multi-step reaction with 2 steps

1: potassium carbonate / acetonitrile / 16 h / Inert atmosphere; Reflux

2: hydrazine hydrate / methanol / 14 h / 70 °C

With potassium carbonate; hydrazine hydrate; In methanol; acetonitrile;

DOI:10.1039/c1cc14041h

upstream raw materials:

2-Methylthiophene

3,5-dibromo-2-methylthiophene

1,2-bis-(5-[4-(2-{2-[2-(2-{2-methoxycarbomethoxy}-ethoxy)-ethoxy]-ethoxy}-ethoxy)-phenyl]-2-methyl-thiophene-3-yl)-perfluorocyclopentene

3-bromo-5-(4-methoxyphenyl)-2-methylthiophene