1,2-bis-(5-[4-(2-{2-[2-(2-{2-methoxycarbomethoxy}-ethoxy)-ethoxy]-ethoxy}-ethoxy)-phenyl]-2-methyl-thiophene-3-yl)-perfluorocyclopentene

Base Information

• Chemical Name: 1,2-bis-(5-[4-(2-{2-[2-(2-{2-methoxycarbomethoxy}-ethoxy)-ethoxy]-ethoxy}-ethoxy)-phenyl]-2-methyl-thiophene-3-yl)-perfluorocyclopentene
• CAS No.: 1147082-58-3
• Molecular Formula: C₄₉H₅₈F₆O₁₄S₂
• Molecular Weight: 1049.11
• Mol file: 1147082-58-3.mol

Synonyms:1,2-bis-(5-[4-(2-{2-[2-(2-{2-methoxycarbomethoxy}-ethoxy)-ethoxy]-ethoxy}-ethoxy)-phenyl]-2-methyl-thiophene-3-yl)-perfluorocyclopentene

Chemical Property of 1,2-bis-(5-[4-(2-{2-[2-(2-{2-methoxycarbomethoxy}-ethoxy)-ethoxy]-ethoxy}-ethoxy)-phenyl]-2-methyl-thiophene-3-yl)-perfluorocyclopentene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1,2-bis-(5-[4-(2-{2-[2-(2-{2-methoxycarbomethoxy}-ethoxy)-ethoxy]-ethoxy}-ethoxy)-phenyl]-2-methyl-thiophene-3-yl)-perfluorocyclopentene

There total 4 articles about 1,2-bis-(5-[4-(2-{2-[2-(2-{2-methoxycarbomethoxy}-ethoxy)-ethoxy]-ethoxy}-ethoxy)-phenyl]-2-methyl-thiophene-3-yl)-perfluorocyclopentene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

2-{2-[2-(2-{2-methoxycarbomethoxy}-ethoxy)-ethoxy]-ethoxy}yl p-toluenesulfonate (872409-96-6) + 1,2-Bis-<5'-(4''-hydroxyphenyl)-2'-methylthien-3'-yl>perfluorocyclopentene (156686-73-6) → 1,2-bis-(5-[4-(2-{2-[2-(2-{2-methoxycarbomethoxy}-ethoxy)-ethoxy]-ethoxy}-ethoxy)-phenyl]-2-methyl-thiophene-3-yl)-perfluorocyclopentene (1147082-58-3)

Guidance literature:

With potassium carbonate; In acetonitrile; at 90 ℃; for 10h;

Reference yield:

3,5-dibromo-2-methylthiophene (29421-73-6) → 1,2-bis-(5-[4-(2-{2-[2-(2-{2-methoxycarbomethoxy}-ethoxy)-ethoxy]-ethoxy}-ethoxy)-phenyl]-2-methyl-thiophene-3-yl)-perfluorocyclopentene (1147082-58-3)

Guidance literature:

Multi-step reaction with 4 steps

1: tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate / tetrahydrofuran

2: n-butyllithium / tetrahydrofuran / 6 h

3: boron tribromide

4: potassium carbonate / acetonitrile / 16 h / Inert atmosphere; Reflux

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; n-butyllithium; boron tribromide; sodium carbonate; potassium carbonate; In tetrahydrofuran; acetonitrile;

DOI:10.1039/c1cc14041h

Reference yield:

3-bromo-5-(4-methoxyphenyl)-2-methylthiophene (156686-75-8) → 1,2-bis-(5-[4-(2-{2-[2-(2-{2-methoxycarbomethoxy}-ethoxy)-ethoxy]-ethoxy}-ethoxy)-phenyl]-2-methyl-thiophene-3-yl)-perfluorocyclopentene (1147082-58-3)

Guidance literature:

Multi-step reaction with 3 steps

1: n-butyllithium / tetrahydrofuran / 6 h

2: boron tribromide

3: potassium carbonate / acetonitrile / 16 h / Inert atmosphere; Reflux

With n-butyllithium; boron tribromide; potassium carbonate; In tetrahydrofuran; acetonitrile;

DOI:10.1039/c1cc14041h

upstream raw materials:

2-{2-[2-(2-{2-methoxycarbomethoxy}-ethoxy)-ethoxy]-ethoxy}yl p-toluenesulfonate

1,2-Bis-<5'-(4''-hydroxyphenyl)-2'-methylthien-3'-yl>perfluorocyclopentene

2-Methylthiophene

3,5-dibromo-2-methylthiophene

Downstream raw materials:

C₄₇H₅₄F₆O₁₄S₂

1,2-bis-(5-[4-(2-{2-[2-(2-{2-hydrazidocarbomethoxy}ethoxy)-ethoxy]-ethoxy}-ethoxy)-phenyl]-2-methyl-thiophene-3-yl)-perfluorocyclopentene