6-bromo-8-methoxy-2-oxo-2H-chromene-3-carboxylic acid

Base Information

Chemical Name:6-bromo-8-methoxy-2-oxo-2H-chromene-3-carboxylic acid
CAS No.:119686-34-9
Molecular Formula:C₁₁H₇BrO₅
Molecular Weight:299.078
Hs Code.:2932209090
DSSTox Substance ID:DTXSID20369500
Wikidata:Q82156613
Mol file:119686-34-9.mol

Synonyms:119686-34-9;6-bromo-8-methoxy-2-oxo-2H-chromene-3-carboxylic acid;6-bromo-8-methoxy-2-oxochromene-3-carboxylic acid;MFCD01764559;2H-1-Benzopyran-3-carboxylic acid, 6-bromo-8-methoxy-2-oxo-;Maybridge1_006711;Oprea1_406814;HMS560J01;DTXSID20369500;AKOS022180498;CCG-247429;SY302031;CS-0335045;FT-0620991;6-Bromo-8-methoxy-2-oxo-2H-1-benzopyran-3-carboxylic acid;6-BROMO-8-METHOXY-2-OXO-2H-CHROMENE-3-CARBOXYLICACID

Suppliers and Price of 6-bromo-8-methoxy-2-oxo-2H-chromene-3-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Apolloscientific
6-Bromo-8-methoxy-2-oxo-2H-chromene-3-carboxylic acid
1g
$ 399.00

Apolloscientific
6-Bromo-8-methoxy-2-oxo-2H-chromene-3-carboxylic acid
250mg
$ 129.00

Total 7 raw suppliers

Chemical Property of 6-bromo-8-methoxy-2-oxo-2H-chromene-3-carboxylic acid

Chemical Property:

Vapor Pressure:6.55E-10mmHg at 25°C
Melting Point:226 °C
Refractive Index:1.638
Boiling Point:477.1°Cat760mmHg
Flash Point:242.3°C
PSA：76.74000
Density:1.785g/cm³
LogP:2.26230
XLogP3:2.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:2
Exact Mass:297.94769
Heavy Atom Count:17
Complexity:378

Purity/Quality:

98%min ^*data from raw suppliers

6-Bromo-8-methoxy-2-oxo-2H-chromene-3-carboxylic acid ^*data from reagent suppliers

Safty Information:

Pictogram(s): R20/21/22:Harmful by inhalation, in contact with skin and if swallowed.; R36/37/38:Irritating to eyes, respiratory system
Hazard Codes: Xn:Harmful;
Statements: R20/21/22:Harmful by inhalation, in contact with skin and if swallowed.; R36/37/38:Irritating to eyes, respiratory system
Safety Statements: S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.; S36/37/39:Wear suitabl

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=C2C(=CC(=C1)Br)C=C(C(=O)O2)C(=O)O

Technology Process of 6-bromo-8-methoxy-2-oxo-2H-chromene-3-carboxylic acid

There total 1 articles about 6-bromo-8-methoxy-2-oxo-2H-chromene-3-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 2033-24-1
cycl-isopropylidene malonate

: 5034-74-2
5-bromo-3-methoxysalicylaldehyde

: 119686-34-9
6-bromo-8-methoxy-2-oxo-2H-chromene-3-carboxylic acid

Guidance literature:: With Glutamic acid; In ethanol; Reflux;
DOI:10.1021/acs.orglett.6b03806

Reference yield:

: 119686-34-9
6-bromo-8-methoxy-2-oxo-2H-chromene-3-carboxylic acid

: 8-methoxy-6-bromocoumarin-3-carboxy-(p-bromo)-anilide

Guidance literature:: Multi-step reaction with 2 steps

1: SOCl₂ / benzene / 3 h / Heating

2: 65 percent / diethyl ether / 3 h

With thionyl chloride; In diethyl ether; benzene;