2-Boc-amino-3,3-diphenyl propionic acid

Base Information

Chemical Name:2-Boc-amino-3,3-diphenyl propionic acid
CAS No.:119363-63-2
Molecular Formula:C20H23 N O4
Molecular Weight:341.407
Hs Code.:
DSSTox Substance ID:DTXSID30392945
Mol file:119363-63-2.mol

Synonyms:119363-63-2;2-Boc-amino-3,3-diphenyl propionic acid;BOC-DL-3,3-diphenylalanine;2-((tert-Butoxycarbonyl)amino)-3,3-diphenylpropanoic acid;boc-3,3-diphenyl-dl-alanine;2-[(2-methylpropan-2-yl)oxycarbonylamino]-3,3-diphenylpropanoic acid;2-((tert-Butoxycarbonyl)amino)-3,3-diphenylpropanoicacid;N-Boc-beta-phenyl-L-phenylalanine;SCHEMBL2187819;DTXSID30392945;2-[(2-methylpropan-2-yl)oxycarbonylamino]-3,3-diphenyl-propanoic Acid;MFCD00797562;AKOS005073830;SS-3920;CS-0171825;FT-0643290;FT-0643350;FT-0679841;FT-0681821;A807416;2-tert-butoxycarbonylamino-3,3-diphenyl-propionic acid;2-[[(2-methylpropan-2-yl)oxy-oxomethyl]amino]-3,3-diphenylpropanoic acid

Suppliers and Price of 2-Boc-amino-3,3-diphenyl propionic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
Boc-DL-3,3-diphenylalanine >95%
1g
$ 454.00

Matrix Scientific
Boc-DL-3,3-diphenylalanine >95%
500mg
$ 362.00

Matrix Scientific
Boc-D-3,3-diphenylalanine
1g
$ 212.00

Matrix Scientific
Boc-D-3,3-diphenylalanine
5g
$ 785.00

Crysdot
2-((tert-Butoxycarbonyl)amino)-3,3-diphenylpropanoicacid 97%
5g
$ 739.00

AstaTech
2-BOC-AMINO-3,3-DIPHENYLPROPIONICACID 97%
0.25 / G
$ 87.00

AstaTech
2-BOC-AMINO-3,3-DIPHENYLPROPIONICACID 97%
1 / G
$ 218.00

AstaTech
2-BOC-AMINO-3,3-DIPHENYLPROPIONICACID 97%
5 / G
$ 763.00

American Custom Chemicals Corporation
2-TERT-BUTOXYCARBONYLAMINO-3,3-DIPHENYL-PROPIONIC ACID 95.00%
0.25G
$ 624.00

American Custom Chemicals Corporation
2-TERT-BUTOXYCARBONYLAMINO-3,3-DIPHENYL-PROPIONIC ACID 95.00%
500MG
$ 791.52

Total 16 raw suppliers

Chemical Property of 2-Boc-amino-3,3-diphenyl propionic acid

Chemical Property:

Vapor Pressure:6.31E-11mmHg at 25°C
Melting Point:133 °C(Solv: hexane (110-54-3))
Refractive Index:1.562
Boiling Point:502.7°C at 760 mmHg
PKA:3.68±0.10(Predicted)
Flash Point:257.8°C
PSA：75.63000
Density:1.167g/cm³
LogP:4.18730
XLogP3:4
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:7
Exact Mass:341.16270821
Heavy Atom Count:25
Complexity:427

Purity/Quality:

97% ^*data from raw suppliers

Boc-DL-3,3-diphenylalanine >95% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)NC(C(C1=CC=CC=C1)C2=CC=CC=C2)C(=O)O
Uses Boc-DL-3,3-diphenylalanine, can be used in the synthesis of ketomethylene pseudopeptide analogs acting as thrombin inhibitors

Technology Process of 2-Boc-amino-3,3-diphenyl propionic acid

There total 7 articles about 2-Boc-amino-3,3-diphenyl propionic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 24424-99-5
di-tert-butyl dicarbonate

: 119273-60-8
2-amino-3,3-diphenylpropanoic acid hydrochloride

: 119363-63-2
2-(N-tert-butoxycarbonylamino)-3,3-diphenylpropanoic acid

Guidance literature:: With sodium hydroxide; In 1,4-dioxane; water; for 2h; Ambient temperature;
DOI:10.1021/jm00096a010

Reference yield:

: 143646-43-9
ethyl acetamido(diphenylmethyl)cyanoacetate

: 119363-63-2
2-(N-tert-butoxycarbonylamino)-3,3-diphenylpropanoic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 82 percent / 20percent aq. HCl / 30 h / Heating

2: 90 percent / NaOH / dioxane; H₂O / 2 h / Ambient temperature

With hydrogenchloride; sodium hydroxide; In 1,4-dioxane; water;
DOI:10.1021/jm00096a010

Reference yield:

: 776-74-9
Bromodiphenylmethane

: 119363-63-2
2-(N-tert-butoxycarbonylamino)-3,3-diphenylpropanoic acid

Guidance literature:: Multi-step reaction with 3 steps

1: 58 percent / t-BuOK / 2-methyl-propan-2-ol / 24 h / 20 °C

2: 82 percent / 20percent aq. HCl / 30 h / Heating

3: 90 percent / NaOH / dioxane; H₂O / 2 h / Ambient temperature

With hydrogenchloride; sodium hydroxide; potassium tert-butylate; In 1,4-dioxane; water; tert-butyl alcohol;
DOI:10.1021/jm00096a010