Technology Process of C52H62N9O12P
There total 6 articles about C52H62N9O12P which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
C43H45N7O11;
With
1H-tetrazole;
In
acetonitrile;
at 20 ℃;
for 0.5h;
N,N,N',N'-tetraisopropyl 2-cyanoethylphosphorodiamidite;
In
acetonitrile;
at 20 ℃;
for 3h;
DOI:10.1021/jo400651k
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: copper(ll) sulfate pentahydrate; sodium L-ascorbate / dichloromethane; water / 3 h / 20 °C
2.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 2 h / 20 °C
3.1: 1H-tetrazole / acetonitrile / 0.5 h / 20 °C
3.2: 3 h / 20 °C
With
1H-tetrazole; copper(ll) sulfate pentahydrate; tetrabutyl ammonium fluoride; sodium L-ascorbate;
In
tetrahydrofuran; dichloromethane; water; acetonitrile;
DOI:10.1021/jo400651k
- Guidance literature:
-
Multi-step reaction with 6 steps
1.1: bromine / acetonitrile / 0.5 h / 0 °C
1.2: 2.17 h / 0 - 60 °C
2.1: potassium carbonate / methanol / 12 h / 20 °C
3.1: pyridine / 12 h / 20 °C
4.1: copper(ll) sulfate pentahydrate; sodium L-ascorbate / dichloromethane; water / 3 h / 20 °C
5.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 2 h / 20 °C
6.1: 1H-tetrazole / acetonitrile / 0.5 h / 20 °C
6.2: 3 h / 20 °C
With
1H-tetrazole; copper(ll) sulfate pentahydrate; tetrabutyl ammonium fluoride; bromine; potassium carbonate; sodium L-ascorbate;
In
tetrahydrofuran; pyridine; methanol; dichloromethane; water; acetonitrile;
DOI:10.1021/jo400651k
